ABO blood Types Flashcards
What controls A1/A2 cells
anti-A1 lectin +/-
Briely describe bombay again
what gene adds….
genotype/blood type
chromosome?
gene FUT1 adds fucose type 2 chains on rbc, genotype H
O blood type
Chromosome 19
A/B
genotype
chromosome
genotype A/B
Hh/HH/hh
Chromosome 9
Blood type %
AB
A
B
O
AB 5%
A 35%
B 15%
O 50%
give examples of antithetical ag
A1 cells/B cells
if a dIscrepcency is detected before a necessary transfusion
eX
transfusion is necessary before resolution, only TYPE O will be used
this would be like if forward/reverse dont match
Hxt doesnt match
ABO ags are what Ig? what do they do
IgM, fix compliment/hemolysis
How do enhance discrepency
use what on forwards type?
use what to verify agglutination?
make it colder (5-15 min)
Use Anti A,B on forwards type
Use saline control for forward type to verify agglutination
Anti-A Anti-B A1 B cells
+4 +4 +1. 0
What is the forward/reverse?
What do you do to enhance?
Forward is AB
Backwards is B
Use A1 lectin on forwards
Use A2 cells on reverse
Anti-A Anti-B A1 B cells
4+ 4+ +1 0
A1 cell
0
what type of blood can you give?
lacks branches
A subgroup
A2B w Ab
can give B/O blood
Anti-A Anti-B A1 B cells
4+ 0 0 0
What is wrong here?
too little….
sometimes immunocomp pt cant…
too little reactivity, MOST COMMON DISCREPENCY
make rxn colder
sometimes immunocomp pt cant make Ab because of irrateated blood products
Anti-A Anti-B A1 B cells
4+ 4+ 4+ 4+
Whats wrong here?
Forwards vs reverse type?
How do you fix?
Forwards AB
Reverse O
too much reactivity
WARM SAMPLE
use saline/wash cells
test against screen cells
Red cell donor selections
A
B
O
AB
What are their donor rbcs?
A: OA (anti-B)
B: OB (anti-A)
O: O
AB: OAB (AB)
Plasma Blood Donor
A
B
O
AB
What are their plasma products?
A: AB, A
B: AB: B
O: AB, O, B , B
AB: AB
What is the universal plasma donor
AB
