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FM1010 > A: Histology of skin > Flashcards

A: Histology of skin Flashcards

1
Q

Identify

A

Stratified squamous

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2
Q

3 layers of skin:

A

Epidermis
Dermis
Hypodermis

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3
Q

Epidermis

A
  • Stratified squamous epithelium
  • Keratinocytes: produce keratin
  • Cells are in layers
  • Separated from dermis by basal membrane
  • Avascular
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4
Q

Stratum corneum

A

Cells are dead: flat sacs filled with keratin
Extracellular space has glycolipid –> waterproof

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5
Q

Stratum granulosum

A

Keratohyaline granules
Cells are flatter
Organelles degenerate and the cell dies

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6
Q

Stratum spinosum

A
  • Intermediate filaments of cytokeratin
  • Desmosomes
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7
Q

Stratum basale

A
  • High mitotic activity
  • Cuboidal cells
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8
Q

Stratum lucidum layer

A
  • only in thick skin
  • inner part of keratin layer
  • thin, clear zone
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9
Q

Desquamation

A

Cells move through deep layers, older cells on surface fall off.

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10
Q

Keratinization

A

Cells move through layers, fill with keratin and die
Surface cells resist abrasion and forms permeability layer

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11
Q

Psoriasis

A

Cells move through epidermal layers in days instead of weeks, so cells pile up on surface before having a chance to mature
White scales: keratin + immature cells

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12
Q

Keratinocyte cells:

A

Most cells, produce keratin

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13
Q

Melanocytes

A
  • produces melanin
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14
Q

Langerhan’s cells

A

Increases inflammatory conditions

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15
Q

Merkel cell

A

Touch receptor

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16
Q

Contact dermatitis

A

Inflammation of skin caused by direct contact with irritating substance.
Skin rash at site of exposure,

17
Q

Dermis papillary layer

A
  • areolar CT
  • Dermal papillae arranged in parallel rows
18
Q

Dermis reticular layer

A
  • Thicker
  • Dense irregular CT
  • Tension lines
19
Q

Hypodermis

A
  • Areolar CT and adipose CT
  • Anchors skin
  • Variable thickness
20
Q

In which layer of the epidermis do cells contain keratohyalin granules?

A

stratum granulosum

21
Q

Identify

A

Dermis, papillary layer

22
Q

Identify

A

Thin skin

23
Q

Identify

A

Hypodermis

24
Q

Identify

A

Stratum granulosum

25
Q

Identify

A

Dermis, reticular layer

26
Q

Identify

A

Stratum spinosum

27
Q

Identify

A

Stratum spinosum

28
Q

Identify

A

Stratum basale

29
Q

Which layer of epidermis is only found in thick skin

A

Stratum lucidum

30
Q

Identify

A

Stratum granulosum

31
Q

Identify

A

Stratum corneum

32
Q

Which cell type of the epidermis is involved in the mediation of immune responses?

A

Langerhans cell

33
Q

Identify

A

Stratum corneum

34
Q

Which layer of the epidermis is responsible for the barrier function of the epidermis?

A

Stratum corneum

35
Q

Identify

A

Stratm granulosum

FM1010 (50 decks)

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