A CH 5 Integumentary system Flashcards
Epidermis
Stratified squamous epithelium that is keratinized
Avascular
The superficial thinner layer
Dermatology
Medical speciality the deals with skin disorders
Dermis
dense irregular connective tissue
Keratinocytes
90% of epidermal cells
Produce keratin which protects from light heat and bacteria
Melanocytes
Are in between keratinocytes
8% of cells
Produce melanin which protects against uv light
Langerhans cells
Arise from red bone marrow and migrate to the epidermis
They are for immune response
Merkel cells
Least numerous of epidermal cells
Detect touch
What are the layers of the epidermis
Stratum corneum Stratum lucidum Stratum granulosum Stratum spinosum Stratum basale
Stratum Corneum
Twenty five to thirty rows of dead, flat keratinocytes that contain mostly keratin
Stratum Lucidum
Only present in skin of fingertips, palms and soles,
Consists of four to six rows of clear, flat, dead keratinocytes with large amounts of arranged keratin
Stratum Granulosum
Three to five rows of flattened keratinocytes, in which organelles are beginning to degenerate
Cells contain protein keratohyalin which converts keratin filaments into keratin, and larger granules which release a lipid rich water repellant secretion
Stratum spinosum
Eight to ten rows of many sided keratinocytes with bundles of keratin intermediate filaments
Contains armlike projections of melanocytes a intraepidermal macrophage cells
Stratum basale
Deepest layer composed of a single row of cuboidal or columnar keratinocytes that contain scattered keratin intermediate filaments
Stem cells undergo cell division to produce new keratinocytes
Melanocytes and tactile epithelial cells associated with tactile discs are scattered among the keratinocytes
Dermis
The second layer, deeper part of the skin
Composed of connective tissue (Areolar- papillary region and dense irregular-reticular region)
Has fibroblasts, macrophages, adipocytes
Blood vessels, nerves, glands, hair follicles
Thick in palms and soles
Thin in eyelids, penis and scrotum
Thicker in posterior body and lateral limbs
Thinner in anterior body and medial limbs
Papillary region
The superficial portion of the dermis (about one fifth)
Consists of Areolar connective tissue with thin collagen fibers and fine elastic fibers
Contains dermal papillae that house blood capillaries, corpuscles of touch, and free nerve endings
Reticular region
The deeper portion of the dermis consists of dense irregular connective tissue with bundles of thick collagen and some coarse elastic fibers
Spaces between fibers contain some adipose cells, hair follicles, nerves, sebaceous glands and sudoriferous glands
Lines of cleavage
Also called tension lines
Indicate the main direction of collagen fibers in the reticular region
Important in surgery especially plastic surgery
Incisions parallel to the lines heal with fine scars
Incisions made across these lines make broad thick scars
Subcutaneous layer
Not actually a layer of the skin
Also called sub q, superficial fascia, hypodermis
Areolar connective tissue and adipose tissue
Contains Pacinian corpuscles (pressure and vibration sensors)
Name the functions of the skin
Regulation of body temperature (thermoregulation) Protection Sensation Excretion Immunity Blood reservoir Synthesis of vitamin D
Regulation of body temperature
Thermoregulation
Changes in blood flow to the skin
Sweating by sudoriferous glands
Protection
Physical barrier to the external environment
Abrasion, bacteria, dehydration, uv light