9: Smooth Muscle Contraction Flashcards
Varicosites
regions of swelling in smooth muscle that are synaptic contacts filled with NTs
What NTs are used in smooth muscle?
ACh, NE, E
Caveolae
shallow depressions of the sarcolemma found in smooth muscle
Phasic smooth muscle
single-unit, only a few fibers with direct synaptic input, have gap junctions, activated by neurons, hormones, or stretch
Tonic smooth muscle
multiunit, each fiber with synaptic input, not activated by stretch
What activates ligand-gated Ca+2 channels that allow Ca+2 to be released from the SR?
inositol triphosphate
What does Ca+2 bind to causing a conformational change?
calmodulin
Mysoin light chain kinase
activated by Ca+2-calmodulin binding to myosin kinase