9. Endocrine System Flashcards
Also known as Hypophysis or Master’s gland
Pituitary gland
Pituitary gland is found in
Hypophyseal fossa of Sella turcica of Sphenoid bone
Pituitary gland is controlled by
Hypothalamus
Other name for Anterior pituitary gland
Adenohypophysis
Other name for posterior pituitary gland
Neurohypophysis
Connects pituitart gland to Hypothalamus
Infundibular stalk
Which is larger, Anterior or Posterior pituitary gland
Anterior
Adenohypophysis communicates with the Hypothalamus via
Hypophyseal portal system
Adenohypophysis secretes what hormones
(A)GP : (B)FLAT
2 portal veins in the body
🔹Liver: Hepatic portal vein
🔹Hypophysis
A vein towards a capillary (exception)
Portal vein
All veins are ___(flow)___ heart
Towards the heart
All arteries are ___(flow)___ heart
Away from the heart
Hormones secreted by Acidophiles or Alpha cells
“(A)GP”
✔️Growth hormone
✔️Prolactin
Other term for Growth hormone
Somatotropin
4 effects of growth hormone
✔️Chondrogenesis
✔️Protein anabolism
✔️Glycogenolysis
✔️Lipolysis
Breakdown of glycogen into glucose
Glycogenolysis
Process of formation of proteins
Protein ANABOLISM
Breakdown of proteins
Protein CATABOLISM (cut)
Glycogenolysis happens during what state? What hormone?
Hypoglycemic state: GLUCAGON
Glycogen to Glucagon = ^ blood sugar
4 Hormones produced during HYPOGLYCEMIC STATE
“GG EC”
Glucagon
Growth hormone
Epinephrine
Cortisol
Hormone involved during HYPERGLYCEMIA
Insulin only
Stimulates MILK PRODUCTION in mammary gland
Prolactin
Hormones secreted by Basophiles or Beta cells
“(B)FLAT”
FSH
LH
ACTH
TSH
Signals release of cortisol from adrenal gland
ACTH
Stimulate:
✔️Estrogen production (females
✔️Androgen binding protein (males)
✔️Gametogenesis (both)
FSH
Stimulates:
✔️Ovulation
✔️Formation of Corpus Luteum
✔️Testosterone production (males)
LH
Stimulates Zon Fasciculata (adrenal cortex) to produce cortisol
ACTH
Stress steroid hormone
Cortisol
Stimulates Thyroid to produce T# and T4
TSH
More potent thyroid hormone
T3
More numerous thyroid hormone
T4
Releasing hormones are controlled by the _____ to stimulate cells of Adenohypophysis to secrete hormones
Hypothalamus –– releasing hormones
Release of GH
Somatocrinin (go for this✨)
or
Growth hormone releasing hormone
Inhibits release of GH
Somatostatin
“SomatoSTOPin”
Release of Prolactin
PRH
Inhibits prolactin release
Prolactin inhibiting hormone / Dopamine
Release of FSH / LH
Gonadotropin releasing hormone
Release of ACTH
Corticotropin releasing hormone
Release of TSH
Thyrotropin releasing hormone
Excessive hormones in the bloodstream will have a _____ on the hypothalamus to prevent disease
–– Hypothalamus detects concentration of hormones in the blood to know if it will increase or decrease it
Negative feedback
Excessive cortisol
Cushing’s syndrome
🔹Moon face + Buffalo hump
🔹Excessive cortisol
Cushing’s syndrome
Deficient cortisol
Addison’s disease
What is seen in Addison’s disease = deficient cortisol levels
Hyperpigmentations
Excessive thyroid hormones
Hyperthyroidism
Deficient thyroid hormones
Hypothyroidism
Hormone secreted by the hypothalamus neurosecretory cells during puberty
GnRH: Gonadotropin releasing hormone
Male GnRH stimulates Adenohypophysis to secrete:
FSH and LH (sa male, sabay yung dalawa)
Male: Target cells of FSH - what is produced
FSH - Sertoli cells - ABP
Male:
Target cells of LH - what is produced
LH - Leydig cells - Testosterone
When testosterone binds to ABP = formation of sperm called
Spermatogenesis
Responsible for SECONDARY male characteristics
Tes2sterone
Increase levels of testosterone has a negative feedback on what hormones (3)
GnRH
LH
FSH
In females: Menstrual cycle..
Hypo GnRH stimulates
Adenohypophysis to secrete what?
FSH
How many days is menstrual cycle
28 days
Target site of FSH in females
Granulsa cells of Primordial follicle
2 parts of Primordial follicle
Oocyte
Granulosa cells
Granulosa cells with FSH =
Production of Estrogen
Production of Estrogen results to
🔹Primary follicle development
🔹Secondary female charac
🔹Slight thickening of endometrial lining
🔹decline in FSH (negative feedback)
2 hormones responsible for Primordial follicle maturation
FSH
Estrogen
Mature Primordial follicle
Graafian follicle
High ESTROGEN stimulates _____
LH secretion
⬆️E = ⬇️FSH = ⬆️LH
LH peak results to _____
Ovulation
What day is ovulation4
Day 14
Release of egg cell towards falloping tube
Ovulation (bec of LH peak)
Ovulation allows maturation of graafian follicle into
Corpus luteum
What is produced by corpus luteum
PIE
Progesterone
Inhibin
Estrogen
🔹Inhibits FSH
🔹thickens endo lining
🔹stimulates PRH secretion
Progesterone and estrogen
Main hormone of corpus luteum for inhibiting FSH
Inhibin
Site where zygote is implanted
Endometrial lining
Progesterone and Estrogen stimulates PRH secretion to Ant pituitary gland to secrete _____
Prolactin: breasts enlargement = milk production
Increase estrogen and progesterone of corpus luteum = prolactin
If fertilization occurs: corpus luteum is
Corpus luteum is maintained
After how many days will the embryo be implanted in the endometrial lining
After 7 to 9 days
Boards: 7✨
If fertilization doesn’t take place: corpus luteum = forms into
Corpus luteum DISINTEGRATES = CORPUS ALBICANS
Corpus albicans has no function (doesn’t produce PIE) = ⬇️PIE = what happens
Menstrual bleeding
Lifespan of Egg cell
24 hrs after ovulation
Lifespan of sperm
3 to 4 days
Negative feedback of ⬇️PIE
⬆️GnRH
⬆️FSH
Hormonal pills are usually taken for how many days
21 days (+7 placebo effect or iron na lang)
Main hormone for pregnancy and menstruation
Estrogen and Progesterone
Doesn’t synthesize hormones but STORES and SECRETES hormones produced by hypothalamus
Posterior pituitary gland / Neurohypophysis
2 Hypothalamic nucleus
Paraventricular nucleus
Supraoptic nucleus
Hormone produced by Paraventricular nucleus
Oxytocin
Hormone for uterine contraction and milk excretion
Oxytocin
Hormone produced by Supraoptic nucleus
Antidiuretic hormone or Vasopressin
Oxytocin and Vasopressin/ADH are stored in the: _____ then secreted into the _____
Posterior pituitary gland then secreted to the blood
Hormone that increases reabsorption of water in the DCT
Reduce excretion of water in the body
Constrict arterioles ncreasing BP
ADH or Vasopressin
Stimulus for Oxytocin release
Stretching of uterus or cervix(neck) = Oxytocin = Contract
And Areola stimulation (nursing infant) = oxytocin = milk excretion
Neck of uterus
Cervix
9mos baby = cervix is stretched = ⬆️Oxytocin = Uterine contraction. what is this reflex that happens during labor
Ferguson reflex