2. Cellular Division and Physiology Flashcards
Phase when cells stop dividing (examples)
- G0 phase
- Cardiac cells
- Neurons
3 phases of interphase
G1
S
G2
Phase: chromosome duplication
Synthesis phase
Division of Somatic cells
Mitosis
Division of Sex cells
Meiosis
Chromatin condenses
Prophase
Align at the equator
Metaphase
Chromosomes split
Anaphase
Chromatid goes back to chromatin.
Cleavage furrow forms
Telophase
Steps 1-4 or PMAT is also called ____
Karyokinesis
Part of mitosis where cytokinesis happens
Telophase
Cytoplasm divides into two
Cytokinesis
What 2 things happen in Meiosis1 prophase1
Synapsis
Recombination
Phenomenon wherein homologous chromosome pair during meiosis
Synapsis
Sharing of DNA of 2 homologous chromosome aka “crossing over” or chiastmata formation
Recombination
End product of Meiosis1
Sperm: 2 diploid
Egg: 1 diploid and 1 polar body
End product of Meiosis 2
Sperm: 4 haploid
Egg: 1 happloid and 3 polar bodies
Only blood supply of the heart
L and R Coronary artery
Decreased blood supply
Ischemia
Loss of blood supply due to obstruction
Infarction
Common cause of infarction
Obstruction of smaller vessels
Other term for Myocardial Infarction
Heart attack
Common cause of death of Myocardial Infarction
Arrythmia (irreg heart beat)
Most common organ assoc. with infarction
Heart
Brain infarction
Cerebrovascular Accident / Stroke
Least involved organ in infarction
Liver
Most common artery involved in stroke
Lenticulostriate artery (branch of middle cerebral artery)
Initial response of heart to hemorrhage
Tachycardia - increase in function to help brain
Total body fluid volume
60% of weight
2 types of blood fluid volume and %
Intracellular fluid: 40%
Extracellular fluid: 20%
Blood volume = ___% of body weight
8%
If blood volume (8%) not maintained it will result to loss of blood flow or _____
Hypovolemic shock or Hemorrhagic shock
Longest phase of cell division
Interphase
Male with barr body
Klinefelter syndrome
44XXY features:
Klinefelter syndrome
- Gynecomastia
- Micropenis
- Taurodontism
Bull’s eye lesion (2 diseases)
Erythema Multiforme
Lyme disease
Loss of blood flow = Tachycardia
Hemorrhagic shock
Obstruction in coronary artery
Myocardial infarction
Movement of molecule from low to high concentration gradient that USES ATP
Active Transport
Types of Passive Transport
Simple
Facilitated
Osmosis
Simple diffusion is aka
Passive diffusion
Movement of solutes from higher concentration to lower conc
Simple diffusion
Reason why gas exchange happens
Simple diffusion
Site of gas exchange
Alveoli
Facilitated diffusion is aka
Carrier-mediated diffusion
A type of passive transport which needs carrier proteins
Facilitated diffusion
Insulin carrying glucose to insulin sensitive cells is what type of passive transport
Facilitated diffusion
3 insulin sensitive cells
Cardiac muscle cells
Smooth muscle cells
Adipocytes
Movement of water across a semi-permeable membrane from LOW to HIGH osmotic pressure
Osmosis
It is determined by the SOLUTES dissolved in the solution
Osmotic pressure
More solutes = ___ osmotic pressure
High
Less solutes = ____ osmotic pressure
Low
High concentration of solute
Hypertonic
Low concentration of solutes
Hypotonic
Solution has the same solute concentration of body cells
Isotonic
Cells in hypertonic solution results to ____
Shrinkage
Cells on hypotonic solution results in ____
Bursting
Used in surgery to irrigate tissues
NSS (0.9% NaCl)
NSS or 0.9% NaCl is used to irrigate tissues during surgery because
It is isotonic, cells won’t burst or shrink
4 examples of Active transport
NaK pump
Proton pump
Exocytosis
Endocytosis
An example of an active transport that is used by the stomach to maintain its acidity
Proton pump
Acidic pH of stomach
pH = 1-3
Meaning of “pH”
Power of Hydrogen
pH = 7
Neutral
pH = < 7
Acidic
pH = > 7
Basic
Acidic = _____ H : _____ Protons
High Hydrogen : High Protons
Basic = _____ H : _____ Protons
Low H : Low protons
Normal pH of blood
7.35-7.45 (ave: 7.4)
Blood has what type of pH
Weak base or slightly basic
Drug of choice for GERD or Heartburn
Omeprazole
Suffix for Proton pump inhibitors
“-prazole”
Type of medication used when px has hyperacidity
Proton pump inhibitors
Most numerous cation in ECF
Na+
Least numerous cation in ECF
K+
Most numerous anion in ECF
Cl-
Least numerous anion in ECF
HCO3-
Least numerous cation in ICF
Na+
Most numerous cation in ICF
K+
Least numerous anion in ICF
Cl-
Prevents sudden change in pH
Buffers
Most important buffer in the blood plasma
Bicarbonate (HCO3-)
Most numerous anion in ICF
Phosphate (PO4-)
2 buffers in the blood plasma
Bicarbonate (HCO3-)
Phosphate (PO4-)
Movement across a cell membrane without using ATP
Passive transport