9/14 .Histology Bone - Dennis (Completed) Flashcards
What gives bone its extreme strength? 4
The addition of bone salts (Ca2+)
What are important functions of bones? 4
Hematopoiesis
Storage
Movement, protection, support
Where within a bone, do we find compact bone? 6
External surface of long and flat bones
Lamellar bone (mature bone)
Where do we find spongy bone? 6
Makes up cancellous or trabecullar bone 🍖
Found deep to compact bone
What is the role of spongy bone (trabeculae)? 6
Houses bone marrow
This bone type can be lamellar or woven
What are the characteristics of lamellar bone? 7
Mature/secondary bone
Regular parallel arrangement of collagen fibers
What are the characteristics of woven bone (nonlamellar)? 7
Immature/primary bone
Loose arrangement of collagen fibers
Lower mineral content
More cells
During repair what bone type forms? 7
Woven bone
What part of the bone contains the epiphyseal plate? 8
The Epiphysis
What do we call the elongated shaft of a bone? 8
Diaphysis
Within a bone, what houses the bone marrow? 8
The medullary cavity
What is the metaphysis of a bone? 8
Spongy/cancellous bone between diaphysis and epiphysis
What forms the border between the epiphysis and metaphysis? 8
The epiphyseal plate/line
What tissue makes up the periosteum? What cells does it contain? 9
Dense irregular CT
Contains osteoblasts
What anchors the periosteum to the endosteum? 9
Anchored by sharpey’s fibers (perforating fibers)
What cells are found within the endosteum? 9
Osteoprogenitor cells
Reticular cells
CT fibers
What is present in the Inner layer (cellular layer) of the periosteum? 10
Osteoprogenitor cells which retain their potential in case of bone injury
What components make up bone matrix? 11
Water - 10%
Organic components
Inorganic components
What are the organic components of bone? 11
Type I collagen
Proteoglycans
Osteocalcin, osteopontin, osteonectin