825 Flashcards
surrounds entire muscle: also known as fasica
epimysium
surrounds fasciculi
perimysium
surrounds myocytes
endomysium
muscle cell membrane; underlies the endomysium
sarcolemma
invaginations of the sarcolemma
transmit action potential into interior muscle cell
closely apposed to sarcoplasmic reticulum
transverse (T) tubules
membranous sac underlying the sarcolemma
responsible for calcium storage, release and uptake
integral to muscle contraction
sarcoplasmic reticulum
bulbous enlargements of the SR
store and release calcium
terminal cisternae
muscle cell membrane
contains sarcoplasm, cellular proteins, organelles and myofibrils
sarcolemma
divided into individual contactile units - sarcomeres thick filaments (myosin) thin filaments (actin) troponon and tropomyosin are located on actin protein
myofibrils
molecular blueprint: specifies and coordinates assembly of structural, regulatory and contractile proteins
molecular spring: links Z disk to Mline of sarcomere, maintains relative position of actin and myosin, contributes to muscle extensibility and passive force development
may also contribure to signal transduction from myofibril to nucleus and other cellular areas
Titin/ Connectin
comprises majority of thin myofilament
arranged in double helix formation
contains myosin binding sites
actin
resides in groove along length of actin protein
blocks myosin binding site under resting conditions
tropomyosin
spaced at regular intervals along length of actin protein
regulates position of tropomyosin relative to myosin binding site
troponin
slow oxidative
Type I
fast oxidative-glycolytic
Type IIa
fast glycolytic
Type IIb
recommended protein intake for sedentary adults
.8 g protein/kgBW/day
recommended protein intake for physically active adult
1 protein/kgBW/day
tendons and myocyte crossbridges
translate stretch into force
series elastic components
collagenous structures
stabilize and protect muscle
parallel elastic components
stretch creates potential energy that can enhance forces produced by contractile elements
stretch-shortening cylce
muscle tension must be developed at adequate intensity and duration
overload
training must stress the muscles, fibers, motor units that need to perform
specificity
disuse results in loss of muscle mass
reversibility