750 Flashcards
results or inferences that systematiclally deviate from the truth “or processes leading to such deviation”
bias
randomization more than 1 group to allow comparison control: subjects and intervention measurement: patient/client impairment, activity limitations, and participation using validated measures systematic data collection and analysis
ideal characteristics of evidence
hierarchy of evidence for articles about therapy
systematic review of RCT RCT systematic review of cohort studies individual cohort studies outcomes research systematic review of case-controlled studies individual case controlled studies case or cohort study expert opinion
what study do you want for diagnosis
cross sectional study
what study do you want for prognosis
prospective study
what study do you want for intervention
RCT
what study do you want for outcome measure
retrospective or prospective study
what study do you want for clinical prediction rule
RCT
prospective study
what is the outcome of an intervention under IDEAL conditions
efficacy
to what extent can an intervention produce the outcome under typical clinical conditions
effectiveness
PICO
patient
intervention
comparison/control
outcome
original research reports such as articles in peer reviewed journals or on websites, theses and dissertations, and proceedings from professional meetings
primary source
textbooks, summaries on web sites, and review papers that contain information based on primary sources of information
secondary sources
the practice of taking someone elses work or ideas and passing them off as ones own
plagiarism
mental images of observable phenomenon described in words. fatigue pain
concepts
a non observable abstraction created for a specific purpose that is defined by observable measures eg QOL, satisfaction
constructs
an organized set of relationships among concepts and constructs that is proposed to explain relationships
theory
a collection of interrelated concepts or constructs that reflect a common theme; may be the basis of a more formal theory
conceptual framework
predictions on the outcomes of a study
hypotheses
predictions of what will happen if the research intervention is successful
Ha: research hypotheses
prediction that no difference or relationship between variable sill be demonstrated based on the research intervention
Ho: null hypotheses
design in which there is only one subject group OR in which randomization to more than one subject group is lacking OR both lacking
controlled manipulation of the subjects is preserved
overall, lower level of control
quasi-experimental design
controlled manipulation of the subjects is lacking
any grouping of subjects is perdetermined and based on naturally occurring subject characteristics or activities
“observational Study”
analysis limited to descriptive statistics
nonexperimental design
quantitative designs
experimental quasi-experimental non experimental within subject analysis between subject analysis
compares repeated measures of an outcome within the same individuals
within-subject designs
compares outcomes between two or more groups of subjects
between subject designs
single point in time or limited time interval
cross-sectional
across and extended period of time
longitudinal
historical data; lack control
retrospective
happens in future; researcher has more controls on inclusion/exclusion and manipulation of variables
prospective
used for questions about prognostic factors
the same group of subjects are followed time, additional groups can be use for comparison
group shares a common characteristic
observational descriptive designs provide results to statistical analysis of the relationship between the prognostic factor and outcomes
time to ensure the outcome occurs is essential
may be prospective or retrospective (prospective have more control)
cohort designs
a retrospective approach
subjects with the outcome are compared to a control group known to be free of the outcome
goal of study is the relative frequency of exposure to the prognostic factor- risk factor identification
case-control designs
measuring the extent to which an intervention produces a desired outcome under ideal condidions
efficacy
measuring the impact of an intervention under usual clinical conditions
effectiveness
included two or more groups to which subjects are randomly assigned
intervention given to one group
results compared for statistical significance of differences
randomized controlled trial RCT
study contains a purposeful intervention with subjects, but lacks a control group or randomization of subjects
quasi-experimental
only one subject undergoes, in alternating fashion an experimental treatment period and a control comparison period
can impose multiple intervention periods to test interaction
single-system designs
human action has meaning to those involved: to understand action, one must grasp the meaning that constitutes the action
interpretivism
and approach to the analysis of texts that stresses how prior understanding of prejudices shape the interpretive process
hermeneutics
understandings of self and reality are based on experience within a cultural backdrop of shared understanding, practices, language, norms
social constructionism
extent that data withing a category agree/dovetail
internal homogeneity
extent that categories are distinct; discreet categories
heterogeneity of data
what the category is called should make sense
internal plausibility
categories together explain the phenomena
external plausibility
a probabilistic sampling method in which each potential subject has an equal chance of being selected
simple random sample
a probabilistic sampling method in which the first subject is randomly selected from a group organized according to a known identifier, then all remaining subjects are chosen based on their numerical distance from the first individual
systematic sampling approach
a proablilistic sampling method in which subgroups of a population are identified and randomly selected to ensure their inclusion in a study
stratified random sample
a probabilistic sampling method in which subjects are randomly selected from naturally occurring pockets of the population of interest that are geographically dispersed
cluster sampling
methods for choosing subjects that do not use a random selection process; the sample may not represent accurately the population from which it is drawn
non probabilistic sampling methods
a non probabilistic sampling method in which investigators select subjects who are readily available
convenience sampling
a non probabilistic sampling method in which the initial subjects in a study recruit additional participants via word of mouth communication
snowball sampling
a non probabilistic sampling in which investigators hand select specific individuals to participate based on characteristics important to the researcher
purposive sampling
the probability that a statistical test will detect, if present, a relationship between two or more variables or a difference between two or more groups
power
the variable that is purposefully manipulated by investigators in an effort to produce a change in outcome
independent variable
the outcome of interest in a study
in intervention studies it is presumed to happen as a result of the manipulation of the IV
dependent variable
a factor other than the independent variable which may influence or confound the dependent variable
confounding variable
a measure that classifies objects or characteristics but lacks rand order and known equal distance between categories
religion
sex
yes/no response
nominal