7 Drugs in Pregnancy Flashcards
1 source for nonmedical used pain killers?
one doctor
is methadone or heroin more likely to cause NAS?
methadone
most used drug in pregnancy?
THC
partial opioid agonist?
buprenorphine
most serious complicaiton of opioid use?
presentation?
overdose
- coma, pinpoint pupils, bradycardia, hyopthermia
narcotic w highest addiction potential? why?
heroin. easily crosses BBB
withdrawal symptoms seen after 3-4 hours after last opioid?
8-14 hours?
1-3 days?
1-3 hrs - drug craving, anxiety, fear of withdrawal
8-14 hrs - anxiety, restlessness, insomnia, yawning, rhinorrhea, lacrimatin, diaphoresis, stomach cramps, mydriases
1-3 days - muscle, GI, heart, chills, fever, piloerection
3 advantages of buprenorphine over methadone?
advantage of methadone?
lower rates of illicit consumption
fewer withdrawal symptoms
lower potential for respiratory depression
methadone better for polypharmacy
drug that precipitates opioid withdrawal?
naloxone
DOC for opiate addicted pregnant women?
methadone
difference bw opiates and opioids?
opiates are natural
opioids are synthetic
3 symptoms seen 3-4 hrs after last dose of opiates?
craving
anxiety
fear of withdrawal
are opiods tetratogenic?
no
drug most common to cause fetal problems other than NAS?
Alcohol
dose of methadone when doc should consider detoxification?
<40mg daily at less than 20 week gestation