21. Antiepileptics Flashcards
type of seizures Phenytoin is DOC for?
all except absence and atonic seizures
2 tetrogenic antiepileptics?
phenytoin
Valproate
type of seizures with aura?
seizures w no aura?
convulsive/partial present
absent in absence, myoclonic
seizure drug that autoinduces metabolism? result?
Carbamazepine.
Half life will reduce
Antiepileptic causing renal stones? use?
Topiramate
used in IIH
hw to prescribe aniepileptics for planned pregnancy? unplanned?
planned = switch drug if on barbs or phenytoin unplanned = do not switch
AE of oxcarbazepine?
Hyponatremia in first 3 months
Drug that worsens myoclonic seizures?
Carbamazepine
5 AEs of phenytoin?
wc require cessation of therapy?
Nystagmus
gingivial hyperplaysia
hirsuitism
Require cessation:
rashes
heme rxns
wt is status epilepticus?
cause of mortality?
tx? tx if first tx fails?
seizure so frequent that a second seizure occurs before 1st has subsided
hypoxia –> brain damage
IV benzos followed by phenytoin
if fails, phenobarbitol/propofol/midazolam/pentobarbital
3 uses for pregabalin?
adjunct antiepileptic
neuropathic pain
diabetic peripheral neuropathy
wt do seizures correlate with?
abnormal EEG activity
seizures with postictus?
all except absence
DOC for absence seizures?
Ethosuximide
2nd line drug for generalized, and complex seizures?
Carbamazepine
