69. Misc Ortho Dz Flashcards
define osteochonrodysplasia
type of constitutive bone/cartilage diseaseoften heritable=abN endochondral and/or intramembranous ossificationdwarfism (disproportionate or proportionate)
T/F most osteochondrodysplasias are disproportionate dwarfism
TRUE osteochondrodysplasias and nutritional deficiencies are disproportionate dwarfismUSUALLY dwarfism w disproportional SHORT limbs
Hemimelia
APPENDICULAR DYSOSTOSEScongenital complete or partial absence of one of more BONESusually unilateralnot always heritable (except Chihuahuas, DSH, Siamese)usually non painfulterminal (transverse, longitudinal)intercalary (transverse, longitudinal)
Hemimelia classification
terminal (transverse, longitudinal)-absence of all or some of the bones of a limb distal to a certain point . intercalary (transverse, longitudinal)-absence of all or some of the middle bones of a limb with the proximal and distal bones still present (middle one is missing)transverse: complete absence across the limbs widthlongitudinal: absence along the medial or lateral side of a limb
radial hemimelia
usually pre-axial (medial) intercalary longitudinalusually unilateral, marked varus, unable to bear weight, flexure deformitysurgery: declaw (palliative), arthrodesis + reconstruct radial defect (graft, distraction osteogenesis), amputate
dimelia
APPENDICULAR DYSOSTOSEScongenital duplication of the whole or part of a limbdog (not seen in cat)figure out which is nonfunctional and amputate it
ectrodactyly
APPENDICULAR DYSOSTOSEScongenital digital cleft formation extending between metacarpal bonesmost btwn 1 and 2 metacarpal bonesunilateral usually of thoracic limbs
polydactyly
APPENDICULAR DYSOSTOSESpresence of one or more extra digitspreaxial (medial); post axial (lateral)normal autosomal recessive trait in St Bernards, Collies—medial pelvic limb
syndactyly
APPENDICULAR DYSOSTOSESlack of ddx btwn two or more digits simple vs complexcomplete vs incomplete
HOD signalment and presentation
2-6 months of ageLarge -giant breed dogs (Weimaraners)Males are 2.3 times more likelyMetaphyseal swelling (distal RU and tibia most common)Often bilateral+/- pyrexia, pain, warmth
List pediatric bone diseases
–Hypertrophic osteodystrophy HOD–Panosteitis–Craniomandibular osteopathy–Retained ulnar cartilagenous core–Legg calve perches disease–Femoral capital physeal dysplasia–Multiple cartilaginous exostoses
Possible etiologies for HOD
Vitamin D insufficiency (scurvy)Heritable (Weimaraners 0.68 inherited immunodeficiency w low Ig)Infection (blood culture)Canine distemper virus
Pathognomonic radio graphic sign of HOD
Lucent line in the metaphysis parallel to a narrow zone of increased radiodensity immediately immediately adjacent to the physiscan also see see metaphyseal “flare” or widening of the bone
Panosteitis signalment and disease progression
Self limiting Inflammatory disease of the bone marrow of long bonesShifting leg lameness w long bone pain5-12 months - up to 5 YO (older than HOD)Large-giant breed Males 4:1eosinophilic inflammation!
Radiographic diagnosis of panosteitis
Early (rare)- decreased radiodensity evident in medullary cavity near nutrient foramen (changes in intraosseous pressure to increase with vascular congestion–maybe from protein accumulation)Later- increase in medullary opacity w granular pattern or w loss of the normal trabecular pattern+/- Periosteal bone formation as it progresses the medullary canal becomes more diffuse and homogenous