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MTAP 2 Hematology Part 1 > 6.1 RBC Morphological abnormalities > Flashcards

6.1 RBC Morphological abnormalities Flashcards

1
Q

Term for abnormal variation in cell size

A

Anisocytosis

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2
Q

Anisocytosis is based on cell Diameter and MCV

T or F

A

T

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3
Q

Normal value for normocytic in cell diameter??

A

6-8 um

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4
Q

Normal value for normocytic in MCV??

A

80-100 fL

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5
Q

Microcytic in cell diameter and MCV

A

<6

<80

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6
Q

MAcrocytic in cell diameter and MCV

A

> 8 um

> 100 fL

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7
Q

Term for variation in hemoglobin content of RBCs?

A

Anisochromia

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8
Q

Anisochromia is based on central pallor and MCHC

T or F

A

T

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9
Q

Normal value for Normochromic in central pallor?

A

1/3 diameter

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10
Q

Normal value for Normochromic in MCHC?

A

32-36%

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11
Q

Hypochromic in terms of Central pallor

A

> 1/3 of diameter of RBC

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12
Q

Hyperchromic in terms of Central pallor

A

Absent of <1/3 of diameter of RBC

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13
Q

Hypochromic in terms of MCHC

A

<32 MCHC

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14
Q

Hyperchromic in terms of MCHC

A

> 36%

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15
Q

Abnormal variation in RBC shape

A

Poikilocytosis

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16
Q

Deep staining large oval cell

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

A

a

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17
Q

Few Irreglarly spaced projections of varying length and width (Irregular and asymmetic

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

A

c

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18
Q

RBC with blunt or pointed, short projections that are evenly spaced (Symmetric)

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

A

d

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19
Q

Associated with Vit B12 deficiency and Folic acid deficiency

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

20
Q

Associated with Severe liver disease, Abetalipoproteinemia

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

21
Q

Associated with Mcleod Syndrome

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

22
Q

Associated with Uremia and Pyruvate kinase deficiency

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

23
Q

Associated with Autoimmune hemolytic anemia and severe burns

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

24
Q

Associated with Bassen-Kornzweig Syndrome

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

25
Q

In Acantocytes, Abetalipoproteinemia is the absence of LDL while Mcleod syndrome is the weak expression of Kell antigens

T or F

26
Q

Also known as Thorn or spur cell

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

27
Q

Also known as Burr cell

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

28
Q

Also known as Bronze cell
a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

29
Q

In Echniocyte, Uremia is the increase in blood urea and creatinine with symptoms of kidney disease

T or F

30
Q

If there is an increase in ure and creatinine but no kidney disease, this is a sign of?

31
Q

Azotememia is an in vitro the resembles?

A

Crenated RBC

32
Q

Hemoglobin concentrated in the center and around the periphery

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

33
Q

Narrow oval cells which shaped like an Egg-shaped or Cigar-shaped

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

34
Q

Slit-like (mouth-like) area of central pallor

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

35
Q

Fragmented RBCs caused by rupture in peripheral circulation

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

36
Q

Associated with Acute alcoholism and Rh Null

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

37
Q

Associated with Thalassemia major and IDA

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

38
Q

Associated with Obstructive jaundice, HB C disease and Thalassemia

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

39
Q

Associated with Microangiopathic hemolytic anemia (MAHA) and severe burns

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

40
Q

MAHA may result to

D__
Hemolytic uremic syndrome
Thrombotic, Thrombocytopenic purpura

41
Q

Also known as Codocyte, Mexican hat and Leptocyte

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

42
Q

Also known as Helmet cell, Keratocyte and RBC fragments

a. Target Cell
b. Stomatocyte
c. Elliptocyte
d. Schistocyte

43
Q

Hemolytic uremic syndrome in MAHA is associated with what bacteria?

A

E. coli 0157:H7

44
Q

Has single pointed extrnsion resembling tear drop or pear

a. Dacryocyte
b. Drepanocyte

45
Q

Crescent-shaped cell; caused by crystallization of Hb S due to ↓ O2 tension

a. Dacryocyte
b. Drepanocyte

46
Q

Associated with primary Myelofibrosis and Myeloblastic anemia

a. Dacryocyte
b. Drepanocyte

47
Q

Associated with sickle cell anemia / Sickle cell-beta thalassemia

a. Dacryocyte
b. Drepanocyte

MTAP 2 Hematology Part 1 (19 decks)

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