1.1 Hematopoiesis Flashcards
Refers to the continuous, regulated process of renewal, proliferation, differentiation and maturation of all blood cell lines
Hematopoiesis
Phases of hematopoiesis:
an Intravascular hematopoiesis that is active in producing primitive erythroblasts
Mesoblastic phase
Mesoblastic phase is also known as embryonic phase / extrauterine phase
T or F
F
Intrauterine
Site of mesoblastic phase?
Blood islands of Yolk SAc
Mesoblastic phase begins at ____ of gestation
19th day
Hemolobin produced in Mesoblastic phase are?
Gower I, II
Portland
An extravascular heatopoiesis that is active in producing erythroblasts, granulocytes and monocytes
hepatic phase
This phase is the production of megakaryocytes
Hepatic phase
Site pf Hepatic Phase?
Fetal liver
Thymus
Spleen
Kidneys
Lymph nodes
Hepatic phase begins at ______ of gestation
5-7th week
Predominant hemoglobin produced in hepatic phase
Hgb F
This phase begins at 4th to 5th month of gestation
Medullary/ Myeloid phase
Site of medullary phase?
Bone marrow
The primary site ofor hematopoiesis for medullary phase includes:
- Skull
- Vertebrae
- Sternum
- Ribs
- Shoulder
- Iliac Crest
- Proximal ends of large bones
T or F
T
By the end of 24 weeks gestation, the bone marrow becomes the primary site of hematopoiesis
T or F
T
