2.5 RBC metabolic pathways

Question 1

Metabolic pathway:

Anaerobic Glycolysis

Answer 1

Embden meyerhof pathway

Question 2

EMP is the main source of ATP which produces about __%

Answer 2

90

Question 3

Metabolic pathway:

Aerobic Glycolysis

Answer 3

Hexose monophosphate pathway (pentose phosphate pathway)

Question 4

PPP detour of glycolysis about __-__%

Answer 4

5-10

Question 5

EMP:

Glucose is catabolized to ___________

Answer 5

pyruvic acid

Question 6

PPP generates NADPH to reduce ______

Answer 6

Glutathione

Question 7

In PPP, ________ protects RBCs from oxidative damage

Answer 7

Glutathione

Question 8

What is the important enzyme for PPP?

Answer 8

Glucose-6-phosphate Dehydrogenase

Question 9

What is the important enzyme for EMP?

Answer 9

Pyruvate kinase

Question 10

EMP produces a net gain of _ molecules of ATP

Answer 10

2

Question 11

This pathway prevents formation of methemoglobin

Answer 11

Methemoglobin reductase pathway

Question 12

Methemoglobin reductase pathway maintains iron in ________ state

Answer 12

Ferrous (Fe2+)

Question 13

Ferric is the normal state of iron which is the reduced form iron

T or F

Answer 13

F

Ferrous

Question 14

If the iron becomes oxidized, becomes Ferric (Fe3+), hemoglobin becomes abnormal (dysfunctional)

T or F

Answer 14

T

Question 15

Important enzyme for Methemoglobin reductase pathway?

Answer 15

Cytochrome B5 Reductase

Question 16

This pathway generates 2-3 DPG

Answer 16

Rapaport Luebering pathway

Question 17

This pathway enhances the delivery of oxygen to the peripheral tissues

Answer 17

Rapaport Luebering pathway