4.1 HB-O2 Dissociation Curve Flashcards
HB-O2 Dissociation Curve describes how the affinity of hemoglobin for oxygen relates to the partial pressure of _______
Oxygen (PO2)
Shape of the Curve?
Sigmoidal Shape (S shape)
Normally, a PO2 of approx. __mmHg results in 50% of oxygen saturation of the Hgb molecule (P50 value)
27mmHg
HB-O2 DISSOCIATION CURVE:
__-axis: Partial pressure of Oxygen
__-axis: Hb-O2 Saturation
X
Y
HB-O2 DISSOCIATION CURVE:
Decrease PCO2
a. Shift to the left
b. Shift to the right
a
HB-O2 DISSOCIATION CURVE:
Decrease Temp
a. Shift to the left
b. Shift to the right
a
HB-O2 DISSOCIATION CURVE:
Decrease H/Alkalosis
a. Shift to the left
b. Shift to the right
a
HB-O2 DISSOCIATION CURVE:
Increase PO2
a. Shift to the left
b. Shift to the right
b
HB-O2 DISSOCIATION CURVE:
Increase Temp
a. Shift to the left
b. Shift to the right
b
HB-O2 DISSOCIATION CURVE:
Increase H/Acidosis
a. Shift to the left
b. Shift to the right
b
HB-O2 DISSOCIATION CURVE:
Decrease 2-3 DPG
a. Shift to the left
b. Shift to the right
a
HB-O2 DISSOCIATION CURVE:
Increase in 2-3 DPG
a. Shift to the left
b. Shift to the right
b
HB-O2 DISSOCIATION CURVE:
Oxygen affinity to Hbg is increased
a. Shift to the left
b. Shift to the right
a
HB-O2 DISSOCIATION CURVE:
Oxygen affinity to Hbg is Decreased
a. Shift to the left
b. Shift to the right
b
HB-O2 DISSOCIATION CURVE:
Oxygen affinity to Tissue is increased
a. Shift to the left
b. Shift to the right
b