4.1 HB-O2 Dissociation Curve Flashcards

1
Q

HB-O2 Dissociation Curve describes how the affinity of hemoglobin for oxygen relates to the partial pressure of _______

A

Oxygen (PO2)

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2
Q

Shape of the Curve?

A

Sigmoidal Shape (S shape)

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3
Q

Normally, a PO2 of approx. __mmHg results in 50% of oxygen saturation of the Hgb molecule (P50 value)

A

27mmHg

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4
Q

HB-O2 DISSOCIATION CURVE:

__-axis: Partial pressure of Oxygen
__-axis: Hb-O2 Saturation

A

X
Y

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5
Q

HB-O2 DISSOCIATION CURVE:

Decrease PCO2

a. Shift to the left
b. Shift to the right

A

a

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6
Q

HB-O2 DISSOCIATION CURVE:

Decrease Temp

a. Shift to the left
b. Shift to the right

A

a

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7
Q

HB-O2 DISSOCIATION CURVE:

Decrease H/Alkalosis

a. Shift to the left
b. Shift to the right

A

a

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8
Q

HB-O2 DISSOCIATION CURVE:

Increase PO2

a. Shift to the left
b. Shift to the right

A

b

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9
Q

HB-O2 DISSOCIATION CURVE:

Increase Temp

a. Shift to the left
b. Shift to the right

A

b

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10
Q

HB-O2 DISSOCIATION CURVE:

Increase H/Acidosis

a. Shift to the left
b. Shift to the right

A

b

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11
Q

HB-O2 DISSOCIATION CURVE:

Decrease 2-3 DPG

a. Shift to the left
b. Shift to the right

A

a

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12
Q

HB-O2 DISSOCIATION CURVE:

Increase in 2-3 DPG

a. Shift to the left
b. Shift to the right

A

b

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13
Q

HB-O2 DISSOCIATION CURVE:

Oxygen affinity to Hbg is increased

a. Shift to the left
b. Shift to the right

A

a

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14
Q

HB-O2 DISSOCIATION CURVE:

Oxygen affinity to Hbg is Decreased

a. Shift to the left
b. Shift to the right

A

b

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15
Q

HB-O2 DISSOCIATION CURVE:

Oxygen affinity to Tissue is increased

a. Shift to the left
b. Shift to the right

A

b

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16
Q

HB-O2 DISSOCIATION CURVE:

Oxygen affinity to Tissue is Decreased

a. Shift to the left
b. Shift to the right

A

a

17
Q

HB-O2 DISSOCIATION CURVE:

Increase Hb F in adult

a. Shift to the left
b. Shift to the right

A

a

18
Q

HB-O2 DISSOCIATION CURVE:

Fever

a. Shift to the left
b. Shift to the right

A

b

19
Q

HB-O2 DISSOCIATION CURVE:

Increase Methemoglobin

a. Shift to the left
b. Shift to the right

A

a

20
Q

HB-O2 DISSOCIATION CURVE:

Increase Carboxyhemoglobin

a. Shift to the left
b. Shift to the right

A

a

21
Q

HB-O2 DISSOCIATION CURVE:

Hypoxic conditions

a. Shift to the left
b. Shift to the right

A

b

22
Q

HB-O2 DISSOCIATION CURVE:

Altitude areas

a. Shift to the left
b. Shift to the right

A

b

23
Q

HB-O2 DISSOCIATION CURVE:

Exercise

a. Shift to the left
b. Shift to the right

A

b