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MTAP 2 Hematology Part 1 > 1.2 Monophyletic theory > Flashcards

1.2 Monophyletic theory Flashcards

1
Q

A Self-renewal, differentiation cell that is the origin of all cells

A

Pluripotential hematopoietic stem cell

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2
Q

What are the multipotential stem cells?

A

Common myeloid progenitor (CFU-GEMM)

Common lymphoid progenitor

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3
Q

A Committed progenitor cells that produces neutrophil

A

CFU-G

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4
Q

A Committed progenitor cells that produces Monocyte/Macrophage

A

CFU-M

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5
Q

A Committed progenitor cells that produces Eosinophil

A

CFU-Eo

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6
Q

A Committed progenitor cells that produces Basophil

A

CFU-Baso

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7
Q

A Committed progenitor cells that produces RBC

A

BFU-e
CFU-e

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8
Q

A Committed progenitor cells that produces Platelet

A

CFU-Meg

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9
Q

CFU-G can be recognizable in microscope

T or F

A

F

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10
Q

Myeloblast is a morphologically recognizable precursors that can be seen in microscope

T or F

A

T

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11
Q

Surface markers for Hematopoietic Stem cell?

A

CD34

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12
Q

Surface markers for Myeloid (CFU-GEMM)

A

CD33

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13
Q

Surface markers for Erythroif (CFU-E)

A

CD 71

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14
Q

Surface markers for T-lymphoid (Pro T-Cell)

A

CD-5/7

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15
Q

Surface markers for B lymphoid (Pro-B cell)

A

CD 10

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16
Q

Surface marker can be detected using?

A

Flow cytometry

17
Q

Pancytopenia is due to low CD__

A

34

18
Q

Hematopoietic Growth Factors:

Pan-Myeloid growth factors

A

G, M-CSF

19
Q

Hematopoietic Growth Factors:

Multipotential colony-stimulating factor

A

IL-3

20
Q

Hematopoietic Growth Factors:

Activating factor and acts in synergy with other factors

A

IL-6`

21
Q

Hematopoietic Growth Factors:

Promotes formation of B cells and for Megakaryopoiesis

A

IL-11

22
Q

Hematopoietic Growth Factors:

For maturation of Megakaryocytes and platelet production

A

Thrombopoietin

23
Q

Hematopoietic Growth Factors:

Growth and differentiation of erythroid precursors

A

Erythropoietin

24
Q

Source of Erythropoietin

A

Kidneys

25
Q

Source of thrombopoietin

A

Liver

MTAP 2 Hematology Part 1 (19 decks)

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