1.2 Monophyletic theory Flashcards
A Self-renewal, differentiation cell that is the origin of all cells
Pluripotential hematopoietic stem cell
What are the multipotential stem cells?
Common myeloid progenitor (CFU-GEMM)
Common lymphoid progenitor
A Committed progenitor cells that produces neutrophil
CFU-G
A Committed progenitor cells that produces Monocyte/Macrophage
CFU-M
A Committed progenitor cells that produces Eosinophil
CFU-Eo
A Committed progenitor cells that produces Basophil
CFU-Baso
A Committed progenitor cells that produces RBC
BFU-e
CFU-e
A Committed progenitor cells that produces Platelet
CFU-Meg
CFU-G can be recognizable in microscope
T or F
F
Myeloblast is a morphologically recognizable precursors that can be seen in microscope
T or F
T
Surface markers for Hematopoietic Stem cell?
CD34
Surface markers for Myeloid (CFU-GEMM)
CD33
Surface markers for Erythroif (CFU-E)
CD 71
Surface markers for T-lymphoid (Pro T-Cell)
CD-5/7
Surface markers for B lymphoid (Pro-B cell)
CD 10
Surface marker can be detected using?
Flow cytometry
Pancytopenia is due to low CD__
34
Hematopoietic Growth Factors:
Pan-Myeloid growth factors
G, M-CSF
Hematopoietic Growth Factors:
Multipotential colony-stimulating factor
IL-3
Hematopoietic Growth Factors:
Activating factor and acts in synergy with other factors
IL-6`
Hematopoietic Growth Factors:
Promotes formation of B cells and for Megakaryopoiesis
IL-11
Hematopoietic Growth Factors:
For maturation of Megakaryocytes and platelet production
Thrombopoietin
Hematopoietic Growth Factors:
Growth and differentiation of erythroid precursors
Erythropoietin
Source of Erythropoietin
Kidneys
Source of thrombopoietin
Liver
