560A PATHOPHYSIOLOGY Flashcards
Apoptosis is
a) genetically programmed self-destruction of cells
b) a condition characterized by a lack of blood flow
c) the loss of a cell’s ability to divide after injury
d) typically reversible
e) programmed elongation of a cell to avoid the effects of radiation
A
The condition in which mature, competent helper T cells from a donor orchestrate an immune response directed against recipient tissues is
a) immediate hypersensitivity
b) graft vs. host disease
c) hyperacute rejection
d) host vs. graft disease
e) chronic rejection
B
An infarct is caused by
a) trauma
b) poisoning
c) endogenous physical agents
d) anoxia
e) a deficiency of dietary factors
D
A characteristic problem in osteoporosis is
a) cartilage degeneration
b) focal infection
c) pathologic fractures
d) atrophy of epiphyseal plates
e) looseness of the joints
C
A lumbar puncture
a) may produce a mild headache
b) may be performed between L3 and L4
c) draws CSF from the extradural space
d) often traumatizes spinal nerves
e) is performed near the vertebra prominens
b) may be performed between L3 and L4
Which of the following would be most likely to result in respiratory alkalosis?
a) kidney disease
b) hyperventilation
c) overuse of antacids
d) chronic obstructive pulmonary disease (COPD)
b) hyperventilation
What are the benefits of EPA/DHA?
Reduces inflammation, eases joint pain, antidepressive benefits, improves insulin sensitivity, reduces cardiovascular risk, lowers blood pressure and triglycerides
What are the ABCDs of a nutritional exam?
Anthropometric, Biochemical, Clinical, Dietary
What is the difference between arteriosclerosis and atherosclerosis?
Arteriosclerosis is the stiffening or hardening of the artery walls. Atherosclerosis is the narrowing of the artery because of plaque build-up.
What is MTHFR?
Methylenetetrahydrofolate reductase, an enzyme needed to metabolize homocysteine; a genetic mutation that may lead to high levels of homocysteine in the blood and low levels of folate and other vitamins.
What does the ratio of reduced glutathione (GSH) to oxidized glutathione (GSSH) within cells measure?
Level of oxidative stress
In healthy cells and tissue, more than 90% of the total glutathione pool is in the _____ form (GSH), with the remainder in the _____ form (GSSG). A(n) _____ GSSG-to-GSH ratio is indicative of oxidative stress.
Options: reduced, decreased, oxidized, increased
Reduced, oxidized, increased
What converts oxidized glutathione (GSSH) to the reduced form (GSH), and which enzyme catalyzes this conversion?
NADPH, glutathione reductase
What is the range for normal blood pH?
7.35-7.45
Which blood pH indicates acidosis?
Below 7.35
Which blood pH indicates alkalosis?
Above 7.45
At the normal pH of 7.40, the ratio of bicarbonate to carbonic acid buffer is:
20:1
When does metabolic acidosis occur, and what is the cause?
The most selective antimicrobial activity (toxic to bacteria but little or no effect on human cells) would be exhibited by a drug that: A. inhibits cell wall synthesis. B. inhibits protein synthesis. C. injures the plasma membrane. D. inhibits nucleic acid synthesis.
A. inhibits cell wall synthesis.
Infections with viruses cause various clinical manifestations. Which of the following is NOT a manifestation of a virus infection?
A. The virus damages or destroys infected cells.
B. Formation of inclusion bodies in infected cells
C. Production of endotoxins
D. The virus causes proliferation of infected cells.
E. The virus infects cells but causes only an asymptomatic (latent) infection.
C. Production of endotoxins
Coccidioidomycosis is generally an acute, self-limited respiratory infection that subsides without treatment, but a more serious, chronic progressive form is often encountered in: A. teenagers B. young male adults C. immunocompromised persons D. middle-aged females
C. immunocompromised persons
An immunoglobulin found in blood that is a clump of five molecules (a pentamer) is: A. IgM B. IgG C. IgA D. IgD E. IgE
A. IgM
Autoimmune diseases are caused by \_\_\_\_\_\_\_\_\_\_. A. autoantibodies B. non-self-antigens C. self-antigens D. cytokines
A. autoantibodies
Which of the following describes an atopic person?
A. An individual with a low T-cell count
B. An individual with a disease of the immune system
C. An individual who is prone to having allergies
D. An individual who rarely has an allergy
E. None of the above
C. An individual who is prone to having allergies