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BDS2 Oral Biology - Histology > (5) pulp > Flashcards

(5) pulp Flashcards

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1
Q

Where is the pulp located?

A

contained within the pulp chamber and the root canals.

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2
Q

Apical, what does the pulp become continuous with?

A

Periodontal ligament

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3
Q

Why can’t you see the apical foremen?

A

It has been cut so you cannot see it

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4
Q

What lines the border of the pulp and dentin?

A

odontoblasts

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5
Q

What is the pulp?

A

connective tissue

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6
Q

What does the pulp contain?

A

nerves fibres and blood vessels

Antigen presenting cells

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7
Q

Where are odontoblasts bigger?

A

At the crown end

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8
Q

Where are the accessory canals located?

A

Apical third of root

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9
Q

What is the main component of the dental pulp?

A

collagen

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10
Q

What is the organisation of the collagen type 1 fibres?

A

Fibrils thinly scattered through the pulp.
* Randomly organized.

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11
Q

What is the organisation of collagen type 1 fibres at the peripherals ?

A

the peripheries, they area parallel to the predentine surface.

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12
Q

When are collagen type 1 fibres parallel and right angled to peripherals?

A
  • At the peripheries, they area parallel to the predentine surface.
  • Right angles to the amelo-dentine junction in mantle dentine (von Korff’s).
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13
Q

What collagen fibre is found in large amounts?

A

type 3

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14
Q

Do type 1 and 3 collagen fibres have a similar organisation?

A

Similar banding pattern as type I.

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15
Q

What fibres are present in the pulp but at smaller level?

A

Collagen type V : present in small amounts. * Collagen type VI: present in small amounts. *

Fibrillin:
* Microfibrils smaller in diameter than collagen.
* Large glycoprotein.

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16
Q

What are the components of the non-fibrous matrix?

A

Glycosaminoglycans.
* Proteoglycans
* Other adhesion molecules.

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17
Q

What cells are present in the pulp?

A
  • Odontoblasts.
  • Fibroblasts.
  • Immune cells.
  • Undifferentiated cells.
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18
Q

What cells are shown here?

A

Odontoblasts

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19
Q

What shape do the fully differentiated odontoblasts take?

A
  • A fully differentiated odontoblast is a polarized columnar cell with a long process inside a tubule.
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20
Q

What links adjacent odontoblasts and other pulp cells?

A

Small processes

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21
Q

Is the pulpal odontoblasts a single cell layer?

A

Yes

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22
Q

How do the odontoblasts attach to the predentin?

A

Odontoblasts form a layer of single cells attached to the predentine by a single process.

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23
Q

Is the pulp highly innervated?

A

Yes

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24
Q

What is the shape of odontoblasts at the root vs coronally?

A

Coronal odontoblasts are columnar in outline, while they are almost cuboidal in the root.

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25
Q

How do odontoblasts appear in oblique sections?

A

Pseudo-stratified

26
Q

Name structures A-C

A
27
Q

What do fibroblasts do?

A
  • They slowly produce fibres and ground substance.
  • Pulp fibroblasts can degrade
    extracellular matrix, matrix turnover

Apoptosis

28
Q

What do fibroblasts produce?

A

Production of growth factors and cytokines.

29
Q

What are examples of immune cells in the pulp?

A
  • T-lymphocytes
  • Macrophages
  • Dendritic antigen presenting cells
30
Q

What cells lie under the odontoblastic layer?

A

Cells layer capable of differentiating into odontoblasts.

31
Q

What are examples of cells capable of differentiating into odontoblasts?

A
  • Pluripotent primitive mesenchymal cells that could differentiate into a variety of cell types.
  • Modifying cell activity by a change in gene expression.
  • Modified fibroblasts???
32
Q

What blood vessels associate with the pulp?

A

Arterioles and venules

33
Q

How do the arteriolar and venues enter the pulp?

A

enter the pulp via the apical foramen and lateral canals.

34
Q

Do the venues and arteriolar have branches?

A

Yes, to reach peripherals

35
Q

Where do the blood vessels branch profusely?

A

once within the coronal pulp chamber.

36
Q
A
37
Q

Where do the odontoblast lie in the pulp?

A

Periphery

38
Q
A
39
Q

What is the composition of water and organic material in the pulp?

A

75% water
25% organic material

40
Q

What is the main component of pulp?

A

Collagen type 1

41
Q

How is the collagen type 1 organised?

A

Randomly

42
Q

What is the orientation of collagen at the peripherals of the pulp?

A

They are parallel to the predentine surface

43
Q

What is the orientation of collagen type 1 fibres at the amelo-dentin junction in mantle dentine?

A

Right angles

Called Von Korff’s fibres

44
Q

What is the precursor of collagen fibres?

A

Alpha chain

45
Q

What composed procollagen?

A

3 alpha chains of collagen

46
Q

How does procollagen become collagen molecule?

A

Procollagen peptides

47
Q

What does a single collagen molecule form?

A

Collagen fibril after assembly

48
Q

What is the second most abundant collagen fibre in the pulp?

A

Collagen type 2

49
Q

What is similar between collagen 1 and 2?

A

The banding

50
Q

What percent of total pulpal collagen is type 2?

A

41%

51
Q

What are the least abundant types of collagen in the pulp?

A

Type V and VI

52
Q

Name the fibres found in the pulp?

A

Collagen 1, 2, 5, 6

Fibrillin:

Microfibrils

Large glycoproteins

53
Q

What are the types of fibrillins found in the pulp?

A

Microfibrils

Large glycoproteins

54
Q

What are the 2 types f adhesion molecules in the pulp?

A

Lamin and fibronectin

55
Q

What occurs here?

A

Mineralisation front

56
Q

How do odontoblasts attach to one another?

A

Different types of cell junctions

57
Q

What are 3 types of cell junctions?

A

Desmosomes

Tight junctions

Gap junctions

58
Q

What is the role of desmosomes?

A

Mechanical union

59
Q

What is the role of tight junctions?

A

Limit permeability, mechanical integrity

60
Q

What is the role of gap junctions?

A

Synchronisation

61
Q

What can pulp fibroblasts degrade?

A

Extracellular matrix

62
Q

What do fibroblasts turnover?

A

Matrix

BDS2 Oral Biology - Histology (27 decks)

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