4.2.2 Chlamydia trachomatis Flashcards

1
Q

What are the 3 biovars?

A

Trachoma

Lymphogranuloma venereum

Mouse pneumonitis

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2
Q

Most common sexually transmitted bacterial pathogen

A

C. trachomatis

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3
Q

What is the Clinical syndromes for A, B, Ba, C?

A

Ocular (Endemic) Trachoma

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4
Q

What is the Clinical syndromes L1, L2, L2a, L2b, and
L3

A

Lymphogranuloma venereum

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5
Q

What is the Clinical syndromes D, Da, E, F, G, H, I, Ia,
J, Ja, K

A

Urogenital infections

Inclusion conjunctivitis

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6
Q

What is the route of transmission for Ocular trachoma?

A

Hand to eye from formites

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7
Q

What is the route of transmission for Lymphogranuloma and Urogenital infections?

A

Sexual

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8
Q

What is the route of transmission for inclusion conjunctivitis

A

Hand to eye/ Infected birth canal

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9
Q

Characterized by having conjunctival scarring and hyperendemic blindness

A

Ocular trachoma

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10
Q

Severe or chronic infection of the lymphatic system (specifically in the genitals)

A

Lymphogranuloma venereum

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11
Q

What bacteria causes Gonococcal urethritis?

A

N. gonorrhoae

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12
Q

What bacteria causes non-gonococcal urethritis?

A

C. trachomatis

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13
Q

Also known as Reactive Arthritis with classic triad syndrome

A

Reiter’s syndrome

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14
Q

Classic triad syndrome?

A

Conjunctivitis

Urethritis

Arthritis

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15
Q

What is the incubation period for Chlamydia trachomatis?

A

4-5 days

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16
Q

What is the Gold standard for Chlamydiae trachomatis?

A

McCoy
Hep-2
HeLA
Buffalo Green Monkey Kidney cells (BGMK)

17
Q

What is the antigen Detection for C. trachomatis?

A

Enzyme linked immunosorbent assay (ELISA)

Direct fluorescent antibody

18
Q

NOTE: DNA probes and Nucleic acid amplification tests is used for Molecular methods

A
19
Q

Is derived from human synovial fluid of an infected person

A

McCoy

20
Q

2 stains used for cell culture?

A

Giemsa’s stains
Immunoflurescense with monoclonal antibodies

21
Q

Cell culture that is originated from Larynx with carcinoma?

A

Hep-2

22
Q

Cell culture that is originated from cervical caner cells

A

HeLA