4.2.2 Chlamydia trachomatis Flashcards
What are the 3 biovars?
Trachoma
Lymphogranuloma venereum
Mouse pneumonitis
Most common sexually transmitted bacterial pathogen
C. trachomatis
What is the Clinical syndromes for A, B, Ba, C?
Ocular (Endemic) Trachoma
What is the Clinical syndromes L1, L2, L2a, L2b, and
L3
Lymphogranuloma venereum
What is the Clinical syndromes D, Da, E, F, G, H, I, Ia,
J, Ja, K
Urogenital infections
Inclusion conjunctivitis
What is the route of transmission for Ocular trachoma?
Hand to eye from formites
What is the route of transmission for Lymphogranuloma and Urogenital infections?
Sexual
What is the route of transmission for inclusion conjunctivitis
Hand to eye/ Infected birth canal
Characterized by having conjunctival scarring and hyperendemic blindness
Ocular trachoma
Severe or chronic infection of the lymphatic system (specifically in the genitals)
Lymphogranuloma venereum
What bacteria causes Gonococcal urethritis?
N. gonorrhoae
What bacteria causes non-gonococcal urethritis?
C. trachomatis
Also known as Reactive Arthritis with classic triad syndrome
Reiter’s syndrome
Classic triad syndrome?
Conjunctivitis
Urethritis
Arthritis
What is the incubation period for Chlamydia trachomatis?
4-5 days
What is the Gold standard for Chlamydiae trachomatis?
McCoy
Hep-2
HeLA
Buffalo Green Monkey Kidney cells (BGMK)
What is the antigen Detection for C. trachomatis?
Enzyme linked immunosorbent assay (ELISA)
Direct fluorescent antibody
NOTE: DNA probes and Nucleic acid amplification tests is used for Molecular methods
Is derived from human synovial fluid of an infected person
McCoy
2 stains used for cell culture?
Giemsa’s stains
Immunoflurescense with monoclonal antibodies
Cell culture that is originated from Larynx with carcinoma?
Hep-2
Cell culture that is originated from cervical caner cells
HeLA
