1.1.2 Haemophilus Influenzae

Question 1

Common name for H. influenzae?

Answer 1

Pfeiffer’s bacillus

Question 2

Virulence factors of Haemophilus influenzae?

Answer 2

Capsule
IgA protease
Outer membrane proteins and LPS
Adherence mechanisms

Question 3

Components of capsule?

Answer 3

Ribose
Ribitol
Phosphate (Polyribitol phosphate)

Question 4

Virulence factor that has the function of Antiphagocytic and Anticomplementary

Answer 4

Capsule

Question 5

How many serotypes o H influenzae?

Answer 5

6 (a-f)

Question 6

What serotype is the most common and potent and leading cause of meningitis in children?

Answer 6

Serotype b (Hib)

Question 7

Paralyzing effect on the sweeping motion of ciliated respiratory epithelium

Answer 7

Outer membrane protein and Lipopolysaccharide

Question 8

What strains that lacks adherent capability usually cause meningitis?

Answer 8

Encapsulated or typable strains

Question 9

What strains that associated with localized infections or may be carried asymptomatically and cause hepatitis media

Answer 9

Non encapsulated or non typable strains

Question 10

In encapsulated strains, meningitis is mostly attack at the ages?

Answer 10

3 months to 6 years old

Question 11

MOT of meningitis for encapsulated strains?

Answer 11

Inhalation (Respiratory tract)

Question 12

Acute inflammation and swelling of epiglottis?

Answer 12

Epiglottits

Question 13

Epiglottits usually affects what age?

Answer 13

2-4 years old

Question 14

Treatment for epiglottits?

Answer 14

Tracheostomy

Question 15

Serious life threatening disease in young children?

Answer 15

Bacterial tracheitis

Question 16

Characteristic of sputum in Bacterial tracheitis?

Answer 16

Purulent sputum

Question 17

Other signs and symptoms of Bacterial tracheitis?

Answer 17

High fever and pseudomembrane

BARKY cough

Question 18

What is the treatment for bacterial tracheitis?

Answer 18

Broad spectrum antibiotic
IV fluids

Question 19

What are the disease for encapsulated strains or invasive diseases?

Answer 19

Meningitis
Epiglottitis
Bacterial tracheitis

Arthritis
Speticemia
Pneumonia

Question 20

What are the localized infections for non encapsulated strains?

Answer 20

Conjunctivitis
Sinusitis
Otitis media

Question 21

Localized disease for bronchitis and pneumonia can be seen in what patient?

Answer 21

Older patients