4.1) Structure of the cell surface membrane Flashcards

1
Q

What is the primary structure of the cell-surface membrane?

A

Phospholipid bilayer

The phospholipid bilayer consists of hydrophilic phosphate heads and hydrophobic hydrocarbon tails.

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2
Q

What is the function of the cell-surface membrane?

A

Controls movement of substances in and out of the cell

It establishes different conditions inside and outside the cell.

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3
Q

Describe the fluid-mosaic model of cell membrane structure.

A

A model that describes the cell membrane as a mosaic of diverse protein molecules floating in or on the fluid lipid bilayer.

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4
Q

What are the characteristics of phospholipids in the cell-surface membrane?

A
  • Hydrophilic heads point outward
  • Hydrophobic tails point inward
  • Form a bilayer structure
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5
Q

What role do phospholipids play in the cell membrane?

A
  • Allow lipid-soluble substances to enter and leave the cell
  • Prevent water-soluble substances from entering and leaving the cell
  • Make the membrane flexible and self-sealing
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6
Q

How are proteins embedded in the cell-surface membrane?

A
  • Some proteins are on the surface of the bilayer
  • Others span the bilayer completely
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7
Q

What are the functions of proteins in the cell membrane?

A
  • Provide structural support
  • Act as channels for water-soluble substances
  • Allow active transport through carrier proteins
  • Serve as surface receptors
  • Help cells adhere together
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8
Q

What is the function of cholesterol in the cell-surface membrane?

A
  • Adds strength to the membrane
  • Prevents loss of water and dissolved ions
  • Reduces lateral movement of phospholipids
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9
Q

What are glycolipids and their function in the membrane?

A
  • Made of carbohydrate and lipid
  • Act as recognition sites
  • Help maintain membrane stability
  • Assist in cell attachment
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10
Q

What are glycoproteins and their role in the cell membrane?

A
  • Carbohydrate chains attached to extrinsic proteins
  • Act as cell-surface receptors for hormones and neurotransmitters
  • Help cells to recognize one another
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11
Q

True or False: All plasma membranes have the same phospholipid bilayer structure.

A

True

The differences in properties arise from the various substances contained within.

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12
Q

Fill in the blank: The hydrophilic heads of phospholipids are attracted to _______.

A

[water]

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13
Q

Fill in the blank: Cholesterol molecules in the membrane help to _______ the movement of phospholipids.

A

[reduce]

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14
Q

What is the significance of the carbohydrate portion of glycolipids?

A

Acts as a cell-surface receptor for specific chemicals

Example: The human ABO blood system operates through glycolipids.

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15
Q

What do carrier proteins do in the cell membrane?

A

Bind to ions or molecules and change shape to transport them across the membrane.

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16
Q

What is the role of surface receptors in the cell membrane?

A

Identify cells and react to specific molecules, such as hormones.

17
Q

What is the overall function of the cell-surface membrane?

A

Controls the movement of substances in and out of the cell.

18
Q

Which end of the phospholipid molecule lies towards the inside of the cell-surface membrane?

A

Hydrophobic tails.

19
Q

What type of molecule is likely to pass through the cell-surface membrane if it is soluble in lipids?

A

Lipid-soluble molecules.

20
Q

What type of molecule is likely to pass through the cell-surface membrane if it is a mineral ion?

A

Channel proteins.

21
Q

Suggest two properties that a drug should possess to enter a cell rapidly.

A
  • Lipid-soluble
  • Small size.
22
Q

True or False: Most molecules can freely diffuse across the cell-surface membrane.

A

False.

23
Q

List three reasons why many molecules do not freely diffuse across the cell-surface membrane.

A
  • Too large to pass through channels
  • Charged and repelled by protein channels
  • Polar and have difficulty passing through non-polar hydrophobic tails.
24
Q

What does the fluid-mosaic model describe?

A

The arrangement and structure of the cell-surface membrane.

25
Q

Why is the cell-surface membrane described as ‘fluid’?

A

Phospholipid molecules can move relative to one another.

26
Q

Why is the cell-surface membrane described as ‘mosaic’?

A

Proteins embedded in the phospholipid bilayer vary in shape, size, and pattern.

27
Q

What role does cholesterol play in the cell-surface membrane?

A

Adds strength.

28
Q

What is the function of glycoproteins in the cell-surface membrane?

A

Acts as recognition sites for chemicals like hormones.

29
Q

Fill in the blank: The cell-surface membrane provides an internal transport system, such as the _______.

A

[endoplasmic reticulum].

30
Q

What is the function of lysosomes in the cell?

A

Isolate enzymes that might damage the cell.

31
Q

What is the significance of ribosomes on the rough endoplasmic reticulum?

A

Protein synthesis.

32
Q

What are the hydrophilic heads of phospholipids?

A

The part of the phospholipid that interacts with water.