4: Water, ions, membranes

Question 1

Why does ionic size not =ionic radius

Answer 1

hydration shell
The smaller the molecule, the bigger the shell
Cuz higher charge density

Question 2

2 examples of secondary active transport proteins

Answer 2

Symporter
Antiporter

Question 3

Example of an antiporter

Answer 3

sodium calcium antiporter

Question 4

4 examples of cys loop receptor family or ligand gated ion channels

Answer 4

nicotinic AChR
GABAa
5HT3 receptor
Inhibitory glycine receptor

Question 5

What is the 5the ligand gated ion channel that isn’t cys loop

Answer 5

Ionotropic glutatmate receptors

Question 6

Hoe many subunits does nicotinic ach receptor have

Answer 6

pentamer of 5 similar subunits

Question 7

Initial ways to see where ACh binding sites weremlocated before imaging

Answer 7

mutagenesis based structur function studies

Put gene into plasmid, mutate certain section, see what happens

Question 8

What is the protein found in snails thats been used as template for other ligand gated ion channels

Answer 8

acetylcholine binding protein

Question 9

2 first pLGIC located in microbes

Answer 9

ELIC - erwinia chyrsanthemi lig gated ion chan, gated by amines

GLIC - gloeobacter violaceus log gated ion chan, gated by protona

Question 10

Ohms law

Answer 10

Voltage = Current x Resistance

Remember, conductance sometimes replaces resistance (is 1/R)

Question 11

Ionic gradient of Na+

Answer 11

inside = 15mM
outiside = 150mM

Question 12

Ionic gradient of K+

Answer 12

inside = 100mM
outside = 5mM

Question 13

Ionic gradient of Cl-

Answer 13

inside = 13mM
outside = 150mM

Question 14

Ionic gradient of Ca2+

Answer 14

inside = 0.002mM
outside = 2mM