4 Oxygen Transport

Question 1

Which immunoglobulin is delivered in Colostrum, and found in the mucous membranes?

Answer 1

IgA

Question 2

Which immunoglobulin is associated with parasitic immunity?

Answer 2

IgE

Question 3

What is the most common Immunoglobulin?

Answer 3

IgG

Question 4

Which immunoglobulin is found on the surface of B-Cells but has a relatively unknown function?

Answer 4

IgD

Question 5

Haptoglobin, Haemopexin and Methemalbumin serve what function?

Answer 5

Cleanup of Haemoglobin debris

Question 6

Where is IgM usually located?

Answer 6

in the intravascular space

Question 7

Which immunoglobulin is a major component of colostrum?

Answer 7

IgA

Question 8

Rare cases of isolated deficiency of which immunoglobulin are found to be associated with no obvious pathology?

Answer 8

IgD

Question 9

Which immunoglobulin is found in the intravascular space and is considered the first immunoglobulin responder?

Answer 9

IgM

Question 10

The morphologic deformity of erythrocytes in Sickle Cell Anaemia is a result of a genetic change in what component of the cell?

Answer 10

Haemoglobin proteins

Question 11

What effect does haemoglobin have on the ability of the blood to carry oxygen?

Answer 11

67-fold increase in capacity

Question 12

Which principle describes the pH effect of oxygen binding and Haemoglobin?

Answer 12

the Bohr effect

Question 13

Why does foetal haemoglobin (HbF) have a different saturation curve to Haemoglobin (Hb)?

Answer 13

So the blood of the foetus can extract oxygen from the blood of the mother

Question 14

IgA appears to function as the primary immunologic barrier in what tissues?

Answer 14

Mucous Membranes

Question 15

Which Immunoglobulin circulates as a pentamer?

Answer 15

IgM

Question 16

Is haemoglobin an absolute requirement for oxygen to be dissolved in the blood?

Answer 16

No

Question 17

Which molecule has the higher affinity for oxygen - Myoglobin, or Haemoglobin?

Answer 17

Myoglobin

Question 18

What is an important allosteric effector of Hb, which is often found in adaptations to high altitude environments?

Answer 18

2,3-Bisphosphoglycerate

Question 19

The two IgA molecules forming dimerized IgA are linked by a molecule called:

Answer 19

J Chain

Question 20

Indicators of anaerobic metabolism such as 2,3-Bisphosphoglycerate have what effect on hemoglobin?

Answer 20

encourage Hb to give up oxygen

Question 21

Which immunoglobulin plays a major part in allergies and atopy?

Answer 21

IgE

Question 22

What protein is a relative of haemoglobin, found only in muscle tissue?

Answer 22

Myoglobin

Question 23

The Bohr effect describes an increased pH causing an increase or decrease in the O₂ affinity of Hb?

Answer 23

Decrease

Question 24

Which immunoglobulin eliminates small, soluble antigenic proteins via enhanced phagocytosis?

Answer 24

IgG

Question 25

IgA is found most commonly in what form?

Answer 25

Dimerized

Question 26

What is the first antibody to be synthesised after an antigenic challenge?

Answer 26

IgM