4: NEUROANATOMY Flashcards
imaginary line drawn thru centre of length of CNS from bottom of SPINAL CORD to front of FOREBRAIN
NEURAXIS
located near/toward HEAD (front end)
ANTERIOR/ROSTRAL
located near/toward TAIL (back end)
POSTERIOR/CAUDAL
toward BACK
DORSAL
above
SUPERIOR
toward BELLY
VENTRAL
below
INFERIOR
toward SIDE of body (away from middle)
LATERAL
toward MIDDLE of body (away from side)
MEDIAL
structures located on SAME side of body
IPSILATERAL
structures located on OPPOSITE side of body
CONTRALATERAL
one one side only
UNILATERAL
on both sides
BILATERAL
CLOSE to body (trunk)
PROXIMAL
FAR AWAY from body (trunk)
DISTAL
signals that move AWAY from CNS
EFFERENT SIGNALS
signals that move TOWARD CNS
AFFERENT SIGNALS
horizontal plane that divides body TOP-BOTTOM
HORIZONTAL PLANE
vertical plane that divides body LEFT-RIGHT
SAGITTAL PLANE
vertical plane that divides body FRONT-BACK
CORONAL (FRONTAL) PLANE
3 layers of tissue that encase the CNS
MENINGES
3 LAYERS OF MENINGES
- DURA MATER
- ARACHNOID SPACE
- PIA MATER
outermost layer of MENINGES (tough + flexible)
DURA MATER
middle layer of MENINGES (btwn DURA/PIA MATERS)
ARACHNOID SPACE
innermost layer of MENINGES that clings to surface of brain (thin + delicate)
PIA MATER
fluid-filled (CS fluid) space that cushions brain (btwn ARACHNOID SPACE + PIA MATER)
SUBARACHNOID SPACE
infection of MENINGES that incr pressure on brain
MENINGITIS
infection of brain itself
ENCEPHALITIS
hollow spaces in brain filled w CSF
VENTRICLES
VENTRICLES OF BRAIN
- LATERAL VENTRICLES
- THIRD VENTRICLE
- FOURTH VENTRICLE
ventricles in centre of TELENCEPHALON
LATERAL VENTRICLES
ventricle in centre of DIENCEPHALON
THIRD VENTRICLE
ventricle btwn CEREBELLUM + DORSAL PONS in centre of METENCEPHALON
FOURTH VENTRICLE
narrow tube connecting 3RD/4TH VENTRICLES located in centre of MESENCEPHALON
CEREBRAL AQUEDUCT
highly vascular tissue that protrudes into all 4 VENTRICLES + produces CSF
CHOROID PLEXUS
small projection of ARACHNOID MEMBRANE thru DURA MATER into SUPERIOR SAGITTAL SINUS that CSF flows thru to be absorbed into blood supply
ARACHNOID GRANULATIONS
clear fluid that fills VENTRICULAR SYSTEM of brain + SUBARACHNOID SPACE surrounding brain + spinal cord
CEREBROSPINAL FLUID
- supports/cushions brain
- provides nutrients
- removes waste
- maintains BBB
FUNCTIONS OF CEREBROSPINAL FLUID
- CSF = produced by CHOROID PLEXUS in LATERAL VENTS
- CSF flows into 3RD VENT where more CSF = produced
- CSF flows thru CEREBRAL AQUEDUCT to 4TH VENT where more CSF = produced again
- CSF leaves 4TH VENT thru small openings that connect w SUBARACH SPACE surrounding brain
- CSF flows thru SUBARACH SPACE around CNS + is reabsorbed into blood supply thru ARACHNOID GRANULATIONS
STEPS OF CIRCULATION OF CSF THRU VENTRICULAR SYSTEM
condition of TOO MUCH CSF bc all/some VENTS = enlarged caused by an obstruction that impedes normal CSF flow
OBSTRUCTIVE HYDROCEPHALUS
type of ventricular tumour
CHOROID PLEXUS PAPILLOMA
CN for smell
- OLFACTORY
CN for vision
- OPTIC
3 CNS for eye mvmt
- OCULOMOTOR
- TROCHLEAR
- ABDUCENS
CN for chewing/touching/pain for mouth
- TRIGEMINAL
CN for face muscles/taste
- FACIAL
CN for hearing/equilibrium
- VESTIBULOCOCHLEAR
CN for taste/BP
- GLOSSOPHARYNGEAL
CN for heart rate/digestion
- VAGUS
CN for swallowing
11: ACCESSORY
CN for tongue mvmt
12: HYPOGLOSSAL
5 SUBDIVISIONS OF BRAIN
- TELENCEPHALON
- DIENCEPHALON
- MESENCEPHALON
- METENCEPHALON
- MYENCEPHALON
3 MAJOR DIVISIONS OF BRAIN
- FOREBRAIN
- MIDBRAIN
- HINDBRAIN
MEMORY TOOL FOR ORDER OF CRANIAL NERVES
Old Opulent Olivia Tries To Absolutely Fucking Vacuum Grandma Virginia’s Ancient House
LATERAL + THIRD VENTRICLES (+ CEREBRAL HEMIS) = located in this major division
in FOREBRAIN
LATERAL VENTRICLES = located in this subdivision
in TELENCEPHALON
THIRD VENTRICLE = located in this subdivision
in DIENCEPHALON
3 main structures in TELENCEPHALON
- CEREBRAL CORTEX
- BASAL GANGLIA
- LIMBIC SYSTEM
2 main structures in DIENCEPHALON
- THALAMUS
- HYPOTHALAMUS
CEREBRAL AQUEDUCT = located in this major division
MIDBRAIN
CEREBRAL AQUEDUCT = located in this subdivision
MESENCEPHALON
2 main structures in MESENCEPHALON
- TECTUM
- TEGMENTUM
FOURTH VENTRICLE = located in this major division
HINDBRAIN
FOURTH VENTRICLE = located in this subdivision
METENCEPHALON
2 main structures in METENCEPHALON
- CEREBELLUM
- PONS
1 main structure in MYENCEPHALON
- MEDULLA OBLONGATA
6 STRUCTURES OF LIMBIC SYSTEM
- AMYGDALA
- HYPOTHALAMUS
- CINGULATE CORTEX
- ANTERIOR THALAMUS
- MAMMILLARY BODIES
- HIPPOCAMPUS
group of nuclei below cortex in FOREBRAIN that = involved in motor control
BASAL GANGLIA
3 NUCLEI OF BASAL GANGLIA
- CAUDATE NUCLEUS
- PUTAMEN
- GLOBUS PALLIDUS
3 DISEASES ASSOC W DAMAGE TO BASAL GANGLIA
- PARKINSONS
- HUNTINGTONS
- TOURETTES
group of nuclei that = largest portion of DIENCEPHALON above HYPOTHALAMUS
THALAMUS
sensory + motor relay centre
FUNCTION OF THALAMUS
2 NUCLEI OF THALAMUS
- LATERAL GENICULATE NUCLEUS
- MEDIAL GENICULATE NUCLEUS
nucleus of THALAMUS that relays info from RETINA to PRIMARY VISUAL CORTEX
LATERAL GENICULATE NUCLEUS
nucleus of THALAMUS that relays in from AUDITORY PATHWAY to PRIMARY AUDITORY CORTEX
MEDIAL GENICULATE NUCLEUS
group of nuclei in DIENCEPHALON beneath THALAMUS
HYPOTHALAMUS
- maintain equilibrium/homeostasis
- regulate food intake
- regulate body temp
- regulate hormones
FUNCTION OF HYPOTHALAMUS
2 COLLICULI OF TECTUM
- SUPERIOR COLLICULI
- INFERIOR COLLICULI
protrusions on top of MIDBRAIN that = part of VISUAL SYSTEM involved in REM
SUPERIOR COLLICULI
protrusions on top of MIDBRAIN that = part of AUDITORY SYSTEM
INFERIOR COLLICULI
“little brain” at back of brain that:
- controls fine motor control/balance
- role in many cog processes
- has IPSILATERAL motor organization
CEREBELLUM
region of METENCEPHALON that:
- connects CORTEX + CEREBELLUM
- has vestibular functions (balance)
- controls sleep + arousal
PONS
Where is the SUPERIOR OLIVE located?
in the PONS
region of MYENCEPHALON that controls reflexes/respiratory/heart rate + contains RETICULAR ACTIVATING SYSTEM
MEDULLA OBLONGATA
system in MEDULLA that controls arousal/attn/sleep-wake cycles
RETICULAR ACTIVATING SYSTEM
hollow tube closed at rostral end that = origin of CNS
NEURAL TUBE
- part of ECTODERM thickens + forms a plate
- edges of plate curl toward each other creating NEURAL GROOVE
- DAY 21: NEURAL GROOVE closes to form NEURAL TUBE
- DAY 28: NEURAL TUBE = closed at rostral end, develops 3 interconnected chambers which become VENTRICLES + tissue surrounding them become FOREBRAIN/MIDBRAIN/HINDBRAIN
STEPS OF GROSS BRAIN DEVELOPMENT IN EMBRYO
When do wrinkles in brain start to form?
7 MONTHS
stem cells lining inside of NEURAL TUBE that give rise to cells of CNS
PROGENITOR CELLS
layer of cells that line inside of NEURAL TUBE which contains PROGENITOR CELLS that divide + give rise to cells of CNS
VENTRICULAR ZONE (VZ)
- cell birth
- cell migration
- cell differentiation
- cell maturation (axon/dendritic growth)
- synaptogenesis (formation of synapses)
- cell death (synaptic pruning)
STEPS OF CELL GROWTH/DEVELOPMENT
special glia w fibres that grow OUTWARD from VENTRICULAR ZONE to surface of cortex that provide guidance for neurons migrating outward during brain development
RADIAL GLIA
growth of dendritic branches
DENDRITIC ARBORIZATION
AXONS grow ____ than DENDRITES do
faster
process where UNNECESSARY neural connections = KILLED OFF
SYNAPTIC PRUNING
protein that promotes survival + without successful contact w another neuron, dendrite will not receive enough
NEUROTROPHIN
cell death
APOPTOSIS