3.6 Flashcards
Specific defences explain
If a pathogen manages to breach non specific defences and enter blood, specific defences are launched that target that pathogen.
What do lymphocytes do as defence
White blood cells involved in the immune response. Respond to specific antigens on invading pathogens. 2 types, T-lymphocyte and B-lymphocyte
What are antigens
Antigens are protein molecules found on membranes of pathogens. Specific shape for specific pathogen.
Explain b lymphocytes
If an antigen binds to a B Lymphocyte, it activates it and causes that lymphocyte to replicate multiple times. After replication the B Lymphacyte produces antibodies. The antibodies bind to the antigens disabling the pathogen.
Antibodies
Antibodies are y shaped molecules that are produced by B lymphocytes. Fit the specific antigen made by pathogen. When they bind to antigens, they disabled and inactivate the pathogen.
How does allergy work
Sometimes B Lymphocytes can become sensitive to antigens on harmless substances, this can cause stimulation of inflammation response
When a cell is infected by pathogen..
Displays antigens of infection on its own membrane.
How do T Lymphocytes work
T lymphocytes spit antigens on infected cells and attach to the outside of them and release proteins that cause the cell to self destruct. This is apoptosis.
What is apoptosis
Programmed cell death. When proteins of the T Lymphocytes diffuse into the cells, they activate self destruct enzymes
Autoimmune disease how does it work in terms of T lymphocytes
In cases of autoimmune diseases, t lymphocytes get activated by normal cells, causing immune system to attack the body’s own cells.
Autoimmune disease example
Type 1 diabetes, t lymphocytes attack and destroy cells that produce insulin in pancreas
How to train immune system
After original infection, some B and T lymphocytes become memory cells. These memory cells allow for a much faster response if same infection returns. This means pathogen destroyed before symptoms appear
HIV
Hiv Attacks and destroys T Lymphocytes.
Without T lymphocytes the body struggles to destroy infected cells meaning infections take longer and longer to heal. HIV can lead to AIDs