33. 조혈 Flashcards

1
Q

Oprelvekin

A

임상용 IL-11 재조합
E.coli
피하주사

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2
Q

Romiplostim

A
Thrombopoietin 효능약
(Mpl 수용체 작용)
펩티드
피하주사
혈소판감소증

골수이형성증후군 환자에서 미분화세포 증가
AML 위험성 증가

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3
Q

Eltrombopag

A

Thrombopoietin 효능약
(Mpl 수용체 작용)
혈소판 감소증
경구용 비팹티드

간독성

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4
Q

경구용 철분제

A

2가철염

ferrous sulfate
ferrous gluconate
ferrous fumarate

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5
Q

비경구용 철분제

A

iron dextran
iron sucrose
sodium ferric gluconate

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6
Q

deferoxamine

A

급성철분 독성에 사용

강력한 철킬레이트 -> 배설 작용 촉진

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7
Q

급성철분 독성 약

A

deferoxamine

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8
Q

만성철분독성(혈색소침착증)

A

deferoxamine (비경구용)

deferasirox (경구용 철 킬레이터)

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9
Q

엽산 결핍 유발 약물

A

methotrexate
trimethoprim
pyrimethamine
(DHFR 억제)

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10
Q

erythropoietin

A

신장 생성
적혈구 분화 증식 촉진

만서신장환자 2차 야기 빈혈
골수억제 작용 있는 항암요법 (수혈 필요성 줄임)
지구력 요하는 운동선수들이 기록 향상 위해 불법적으로 사용

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11
Q

filgrastim

A

rHU G-CSF
세균발현계
뼈통증 (투여중단시 사라짐)

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12
Q

pegfilgrastim

A

rHu G-CSF
세균발현계
뼈통증 (투여 중단시 사라짐)

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13
Q

sargramostim

A

rHu GM-CSF
효모발현계
더 심한 부작용

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