26/10 - 5.Vancomicina Flashcards

1
Q

puede causar:

A

síndrome del cuello rojoo del hombre rojo

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2
Q

mecanismo de acción:

A

inhibe la síntesis de PARED de bacterias sensibles

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3
Q

evitan el proceso de polimerización: mediante:

A

al unirse ocn gran afinidad al extremo terminal D-Alanil D-Alanina de las unidade sprecurdsoras de la pared

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4
Q

altera la permeabilidad d ela membrana?

A

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5
Q

ínhibe síntesis de ARN?

A

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6
Q

se usan para gram - ?

A

por su gran tamaño, no pueden penetrar la membrana externa de bacterias gram -

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7
Q

espectro útil:

A
pyogenes
strepto pneumoniae
aureus
faecalis
enterococcus faecium
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8
Q

espectro útil amplico contra:

A

gram +

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9
Q

son resistentes en general los

A

gram -

micobacterias

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10
Q

tiene espectro útil contra anaero y aero

A

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11
Q

sirve contra c difficile y listeria mono

A

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12
Q

c max

A

20 a 50 mg/L

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13
Q

semivida plasmática:

A

4 a 8 hrs

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14
Q

vida en plasma con insuficiencia renal grave? IRG

A

44 a 440hrs

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15
Q

usos terapéuticos:

A

infecciones de piel y partes blandas
huesos
articulaciones
osteomielitis

infecciones de vías respiratorias: neumonía por MRSA dosis altas

infecciones del SNC meningitis por strepto pneumoniae altas dosis

endocarditis e infecciones del catéter en vasos: estrepto viridans y crynebacterium y bacillus

colitis pseudomembrnosa c difficile VO

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