2 Skin Flashcards
and Integumentary System
- covering membrane,
- lining membrane
Epithelial membrane
3 Epithelial membrane
- cutaneous membrane
- mucous membrane
- serous membrane
2 membranes of skin
- epithelial membrane
- connective tissue membrane
2 tissues of cutaneous membrane
- epidermis - squamous epithelial tissue
- dermis - dense irregular connective tissue
superficial epithelial membrane
cutaneous membrane
cutaneous membrane layer
- squamous (no vascular) epithelial tissue
epidermis
cutaneous membrane layer
- dense irregular connective tissue,
- vascularized
- gives nutrients to epidermis
dermis
- resting on loose (areolar) connective tissue (lamina propia)
- have mucosae for protection (due to moist to tissues) and secretion
Mucous membrane
this membrane type lines all body cavities that open to the exterior
mucous membrane
- simple squamous epithelium;
- has serous fluids to protect epithelial membrane (serosal membrane – interconnects specific organs);
- shaped based on shape of the organ
Serous membrane/ serosa
- held organs in place
- forms internal visceral layer which covers the outside of the organ in that cavity
- underlies ventral body cavity,
Serous membrane/ serosa
- reduce friction between the organs and the body cavities they occupy thru serous fluid
Serous membrane/ serosa
membrane covers body
cutaneous membrane
membrane that line body cavities closed to exterior
serous membrane/ serosa
- loose areolar (not much fiber - only for fibrous capsules surrounding joints for lubrication),
- secretes lubricating fluid,
- no epithelial,
- cushion organs
Synovial membrane
These membranes line the fibrous capsules surrounding joints providing a smooth surface
and secreting lubricating fluid
Synovial membrane
They also line small sacs of connective tissue called bursae and the tubelike tendon sheaths.
Synovial membrane
Integumentary System Functions
- protection
* mechanical damage
* chemical damage
* microbe damage
* UV
* thermal damage
* dessication - temperature
- excretion
- synthesized vit D
Mechanical damage
* physical barrier,
* protects from bumps, _ (helps in water perspiration) &
* _ – stretch; receptors; tough cells
keratin
elastin
b. Chemical damage – skin is impermeable due to _ but can be permeable depending on kind of acid
keratin
because skin is intact, no entry of bacteria
c. Microbe damage
melanocyte produces melanin to protect from
d. UV
e. Thermal damage - have _
thermal receptor
f. Desiccation - have _ for water retention, barrier
glycolipid
- Temperature – _ release and close to conserve heat
skin pores
excretion of body wastes such as
sodium, urea, uric acid
Synthesis of Vitamin D by converting _ into vitamin D by exposure to _
modified cholesterol - cholecalciferol
sunlight
3 skin structure
outer epidermis
dermis
hypodermis
- stratified squamous epithelium,
- hard and tough,
- have own strata
- Outer epidermis
store fat deposit, adipose tissue
- Hypodermis
- not considered part of skin
- anchor skin to underlying organs
- provides a site for nutrient storage
Hypodermis
strata of epidermis
- stratum basale
- stratum spinosum
- stratum granulosum
- stratum lucidum
- stratum corneum
- stratum where the stem cell continuously dividing;
- some newly formed cells become part of the more superficial layers
- Stratum basale
- stratum with thick/high pigment, intermediate filament made of pre-keratin;
- has dendritic cells
Stratum spinosum
- stratum is flattened,
- cytoplasm full of granules
- organelles are deteriorating
Stratum granulosum
stratum where cells begin to die
Stratum lucidum
- stratum where vessels are present,
- dead cells (present and thickest in palmar and plantar)
- flat membranous sacs filled with keratin
Stratum corneum
Cells in Epidermis
- keratinocytes
- melanocytes
- langerhans cells
- merkel cells
- basal cells
- dendritic cells
the _ of stratum corneum in extracellular space make skin water-resistant
glycolipid
cells for immunity; detects pathogens
Langerhans cells
- cells which are light/ hard touch; sensitive to touch
- connect to nerve endings in the dermis
Merkel cells
- vascular,
- strong, help the body bind together
- connective tissue, stretched enveloped,
Dermis
two major regions of dermis
papillary layer - areolar connective tissue
reticular layer - dense irregular connective tissue
- superficial,
- touch & pain receptor;
- dermal papillae (formed looped, whorled structure for gripping; increases friction and grasp);
- evolutionary adaptation of primates (in palm only)
Papillary layer
- deepest skin layer,
- have collagen and elastic fibers,
- blood vessels, sebsory neurons
- oil & sweat glands;
- _ - deep pressure receptor
Reticular layer
lamellar corpuscles
How many Skin Receptors in skin
one square inch of the skin = 14 receptors
skin receptors
Meissner’s corpuscles
Merkel disc
Root hair plexus
Pacinian corpuscles
Ruffini’s endings
Krause’s end bulbs
- light touch and texture
- fine vibration
Meissner’s corpuscles
Respond to sustained touch and pressure
Merkel disc
wrapped around the base of hair follicles; detect light touch and vibrations when the hair moves
Root hair plexus
Detect deep pressure and fast vibrations
Pacinian corpuscles
- hair stands - cold
- hair leans - hot;
erector muscles present in skin hair for what?
Thermoregulation in skin
Skin color – due to deposits of _ for protection from UV
melanin
deprivation of oxygen
Cyanosis - peripheral cyanosis
Effects of Emotions to skin
- Redness / Erythema
- Pallor/ Blanching
- Jaundice/ Yellow cast
- Bruises – black/ blue marks
embarrassment, fever, hypertension, inflammation, allergy; due to blood rush
Redness / Erythema
fear, anger, anemia, low blood pressure, impaired blood flow causing paleness
Pallor/ Blanching
what forms hair
epithelial root sheath
yellow skin; excess bile pigment (bilirubin) in blood, circulates throughout the body and becomes deposited in body tissues, liver disorder
jaundice/ Yellow cast
black/ blue marks – internal blood clotting; blood escapes circulation and clotted in tissue spaces, blood clotting called _
Bruises
hematomas
2 cutaneous glands
- sebaceous gland
- sweat gland
2 glands of sweat glands
- eccrine
- apocrine
- oil glands,
- sebum (oily substances mixed with fragmented cells) - for lubrication and protection; prevents hair from getting brittle
- absent in hands & soles,
Sebaceous gland
sweat, regulates body temperature, tubular
Sweat glands
- own path;
- body heat regulates sweat when high temperature;
- secretes clear water with salt, vitamin C, metabolites, urea;
- sweat is acidic pH 4-6 inhibiting bacterial growth
Eccrine
- no path;
- axillary & genital;
- releases fatty acids, proteins in hairs;
- milky/ yellowish color; odorless
Apocrine
Sweats are rich in proteins - bacteria use fatty acids and protein as nutrient source to break down causing unpleasant odor
hair are produced by
hair follicles
what forms hair
epithelial root sheath
- Modified skin; Scale-like epidermis
Nail
Infections of skin
- Athlete’s foot
- Boils & carbuncles
- Cold sores (fever blisters)
- Contact dermatitis
- Impetigo
- Psoriasis
- Burns
- Basal cell carcinoma
- Squamous cell carcinoma
- Malignant melanoma
- caused by Tinea pedis (fungus; indigenous microflora),
- prolonged antibiotic
Athlete’s foot
alipunga
- inflammation of hair follicles and surround tissues
- also known as furuncles
- caused by S. aureus
Boils
carbuncles
pigsa
- human herpes virus 1 infection occurs around lips, nose, and mucosa of the mouth;
- emotional upset, fever, UV
Cold sores (fever blisters)
- itching, redness and swelling of skin due to chemicals (poison ivy);
- progressive blistering,
- allergic responses
Contact dermatitis
- staphylococcus & streptococcus,
- contagious;
- pink;
- fluid-filled;
- raised lesions;
- internal fluids
Impetigo
autoimmune disorder; reddened epidermal lesions
Psoriasis
tissue death and cell death caused by sunburn, acid, UV, electricity; tissue damage and cell death
Burns
burn at superficial epidermis; sunburn
1st degree
burn at epidermis & superficial dermis injury
2nd degree
regowth of epithelium can occur
burn at epidermis, dermis to subcutaneous tissue; gray-white/ blackened area
3rd degree
burn at bone, muscle, tendon; require surgery/ grafting; full thickness burn extended to tissue
4th degree
a piece of skin transplant from gluteal (still based on compatibility)
Skin graft
loss/ removal of body part
Amputation
- least malignant,
- common skin cancer;
- cells of stratum basale;
- no longer form/ have keratin;
- metastasized (one spot) is seldom
Basal cell carcinoma
kinds of Basal cell carcinoma
a. Pigmented BCC
b. Nodular BCC
c. Superficial BCC
d. Morphoeic BCC
e. Basosquamous BCC
at stratum spinosum; damages adjacent cell; exposure to UV; reddened papules
Squamous cell carcinoma
melanocyte cancer, pigmented moles
Malignant melanoma
ABCDE in Malignant Melanoma
A Asymmetry
B Border irregularity
C Color
D Diameter
E Evolution
- _ - downy type of fetus hair on 4th - 5th stage
Lanugo
- _ - oily coating; sebaceous gland produces cheesy-looking substances
Vernix caseosa
protect baby skin floating water-filled sac
oil/ Sebaceous gland
- At adolescence - skin & hair become _ as sebaceous glands are activated
oilier
- Acne subsides during _ (early 25 - 30)
early adulthood
- As we age - subcutaneous tissue _ so we become more sensitive to cold; drier due to decrease in _ causing skin itchiness and sogginess
decreases
oil-producing
- Thinning of skin - susceptible to _
bruising
- Decreased in elasticity - _ of subcutaneous forming eye bags
loss
- Smoking & sunlight speeds up decrease in _
elasticity
- Hair losses faster as we age, at 50 hair follicle drop _ ,
- condition as alopecia,
- men baldness ( _ remains) is genetically controlled
- gray hair
⅓
vellus hair