1st Bi Recalls Flashcards

1
Q

Lidocaine exerts its numbing effect as a topical anesthetic by this mechanism:
Activation of potassium channels
Inhibition of sodium channels
Activation of chlride channels
Inhibition of calcium channels

A

Inhibition of sodium channels

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2
Q

An H1 antihistaminic with sedative, antiemetic, antimuscarinic, and spasmolytic properties:
Buspirone
Chlordiazepoxide
Hydroxyzine
Propranolol

A

Hydroxyzine

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3
Q

Ipratropium can be indicated in which of the following clinical conditions?
Hypertension
Heart failure
Bronchial asthma
Peptic ulcer disease

A

Bronchial asthma

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4
Q

Its mechanism of action as an antiseizure drug is its ability to block sodium channels:
Pnenytoin
Valproic acid
Carbamazepine
Phenobarbital

A

Pnenytoin
Valproic acid
Carbamazepine

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5
Q

Abdominal colic is most appropriately managed by the use of this drug:

Hyoscine
Baclofen
Tramadol
Mefenamic acid

A

Hyoscine

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6
Q

Carlo is a 58-year old soldier who has difficulty in urination due to benign prostatic hyperplasia. Which drug can be used to promote urination?
Ergometrine
Sildenafil
Clonidine
Tamsulosin

A

Tamsulosin

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7
Q

A drug that has a wide therapeutic index means that it is:
Safe
Long duration of action
Potent
Short onset of action

A

Safe

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8
Q

This refers to the process of the drug moving into the bloodstream from the site of administration:
Absorption
Bioavailability
Digestion
Distribution

A

Absorption

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9
Q

There is evidence suggesting cannabis can be medically used to:

Reduce the elevated intra-ocular pressure of glaucoma
Treat chronic pain and muscle spasms
Decrease appetite
Reduce nausea and vomiting during chemotherapy

A

Reduce the elevated intra-ocular pressure of glaucoma
Treat chronic pain and muscle spasms
Decrease appetite
Reduce nausea and vomiting during chemotherapy

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10
Q

A condition in which repeating the same dose of a drug produces a smaller effect:

Negative reinforcement
Desensitization
Tolerance
Antagonism

A

Tolerance

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11
Q

During an elective abdominal surgery under general anesthesia, the patient was noted to have muscle rigidity, hyperpyrexia, and tachycardia. Which drug is most important to immediately administer?
Atracurium
Dantrolene
Succinylcholine
Baclofen

A

Dantrolene

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12
Q

The maximum amount (ml) of lidocaine 2% that can be safely injected into a 10- kg child during minor surgery is:
2
1
3
4

A

2 …??

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13
Q

Drugs used in the management of bipolar disorder:

Carbamazepine
Valproic acid
Lithium
Olanzepine

A

Carbamazepine
Valproic acid
Lithium
Olanzepine

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14
Q

Effects of Benzodiazepines include:
Sedation
Retrograde amnesia
Anticonvulsion
Anxiolysis

A

Sedation
Retrograde amnesia
Anticonvulsion
Anxiolysis

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15
Q

These are the effects of Morphine:

Miosis
Nausea and vomiting
Respiratory depression
Diarrhea

A

Miosis
Nausea and vomiting
Respiratory depression

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16
Q

The following drugs can be used to manage dyskinesia of Parkinson’s Disease:
Rasagiline
Pramipexole
Dopamine
Benztropine mesylate

A

Rasagiline
Pramipexole
Dopamine
Benztropine mesylate

17
Q

A drug is eliminated by first-order kinetics. Which of the following statements best describes the process by which the plasma concentration of this drug declines?

Increase in rate of metabolism as drug concentration increases
Constant amount of drug metabolized per unit time
Rapid redistribution
Single metabolic pathway for drug biotransformation

A

Increase in rate of metabolism as drug concentration increases

18
Q

After several minutes of inhalation of this solvent (glue sniffing), dizziness and intoxication can occur:

Nitrous oxide
Kerosene
Toluene
Amyl nitrite

A

Toluene

19
Q

This drug partially stimulates nicotinic receptors thereby reducing nicotine craving and preventing most withdrawal symptoms; however, has also been linked to the risk of developing suicidal ideation:
Varenicline
Bupropion
Methadone
Lofexidine

A

Bupropion

20
Q

A COPD patient with chronic cough and upper back pain was prescribed orphenadrine. The purpose of the drug was to manage which condition:

Bronchoconstriction
Increased airway secretions
Inflammation
Muscle strain and spasm

A

Muscle strain and spasm