1B: Local Anesthetics Flashcards
drugs that cause reversible
block of nerve conduction producing transient
localized anesthesia without significantly affecting
consciousness
local anesthetics
SATA
The basic chemical structure of a local anesthetic
molecule consists of:
a. covalent bond
b. hydrophilic group
c. lipophilic group
d. intermediate bond
B
C
D
Local anesthesia affect fibers in neuron in what sequence
touch
pressure
sensory
cold
motor
Sensory
Cold
Touch
Pressure
Motor
True or false
Calcium antagonize the action of LA
True
TRue or false
K enhances the action of LA
True
TRue or false
Increase extracellular pH increases the action of LA
True
By direct application for skin and mucous membrane
a. SUrface anesthesia
b. INfiltration anesthesia
c. nerve block anesthesia
d. sympathetic block
Surface Anesthesia
By injection close to the appropriate nerve trunk (Brachial plexus) to produce loss of sensation peripherally
a. SUrface anesthesia
b. INfiltration anesthesia
c. nerve block anesthesia
d. sympathetic block
Nerve block
By SC injection to reach fine nerve branches and sensory nerve terminal
a. SUrface anesthesia
b. INfiltration anesthesia
c. nerve block anesthesia
d. sympathetic block
infiltration anesthesia
By injection around spinal roots as they emerge
a. EPidural anesthesia
b. Spinal anesthesia
c. Para vertebral block
d. sympathetic block
para vertebral block
SATA
Onset Of action of LA is related to
a. pKa
b. dose
c. concentration
d. potency
pKa
dose
concentration
true or false
Highly lipid soluble local anesthetics generally have a shorter
duration of action
false
LOnger
True or false
at low dose of LA, vasoconstriction is noted
true
True or false
at high dose of LA, vasodilation is noted
true
The uptake of local anesthetic from greatest to
least is as follows:
tracheal
iV
caudal
intercosta
brachial
epidural
paracervical
sciatic
subcutaneous
IV
Tracheal
Intercostal
Caudal
Paracervical
Epidural
Brachial
SCiatic
SUbcutaneous
