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Cardiopulmonology > (17) Gas Transport (Karius) > Flashcards

(17) Gas Transport (Karius) Flashcards

1
Q

How is [Oxygen] Alveolar determined?

A
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2
Q

How much O2 can dissolve in water?

A

NOT MUCH!!!

Only 0.3 ml O2/dl blood

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3
Q

If the PaO2 is 100mmHg, each dL of blood will carry…

A

0.3 ml O2

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4
Q

In order to meet our metabolic demands (250 ml O2/min), our hearts would have to pump…

A

83 L of blood per min

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5
Q

When we refer to the PaO2, we are referring to…

A

the DISSOLVED OXYGEN

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6
Q

How does our body compensate for the low solubility of O2?

A

Use of HEMOGLOBIN

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7
Q

How many sites does hemoglobin have to bind to O2?

A

4

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8
Q

Important takeaways?

A
  • Cooperative
  • Increased affinity
  • Non linear
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9
Q

At an PO2 greater than 60…

The Hb is at least…

A

85% saturated with oxygen

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10
Q

What is our typical oxygen content at 85% saturation?

A

17 ml O2/dl blood

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11
Q

What does a left shift represent on a Hb-O2 curve?

A

Increase in affinnity of Hb for O2

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12
Q

What does a right shift on the Hb-O2 curve represent?

A

Decrease in the affinity of Hb for O2

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13
Q

What factors can produce shifts in the Hb-O2 curve?

A
  • CO2 and or pH (Bohr effect)
  • Temperature
  • Certain metabolites (2,3 DPG)

*Everything is Right shifted EXCEPT for low CO2/high pH

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14
Q

Where do we see an increase in…

CO2/H+

Temperature

2,3 DPG?

A

In the Tissue

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15
Q

Venous PO2 is…

A

40 mm Hg

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16
Q

What is the O2 saturation of venous blood?

A

Approx. 75%

15.2 ml O2/dl blood

Explains why we can do CPR

17
Q

How do you determine how much oxygen was used by the tissue being perfused?

A

The difference between the

Arterial O2 content and the Venous O2 content

18
Q

The greater the a-v O2 difference is…

A

The higher metabolic demand of the tissue

19
Q

If the fuel is only carbohydrates…

There is a ______ ratio

A

1:1 Ratio

20
Q

If the fuel is exclusively fats…

The ratio is ______

A

7: 10
(0. 7)

21
Q

Usually a mix of fuels:

Carbohydrates and fats produces a…

____ ratio

A

0.8

22
Q

How do you calculate the respiratory quotient (RQ)?

A
23
Q

What is a normal respiratory quotent?

A
24
Q

Answer

A
25
Q

What are the three ways to carry CO2 in the blood?

A

Dissolved CO2

Carbamino compounds

As HCO3

26
Q

How much CO2 can you dissolve in the plasma?

A

6 ml O2 dL blood / 100mm Hg

27
Q

What is the haldane shift?

A

Presence of O2 on the heme reduces the affinity of the Hb chain for the CO2

28
Q

How much CO2 is carried via carbamino compounds?

A

3ml/dl of blood

29
Q

Most of the CO2 in the blood is carried as…

A

Bicarbonate (HCO3)

30
Q
A
31
Q
A
32
Q
A

Cardiopulmonology (22 decks)

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