(11) Alveolar Gas Exchange Physiology (Karius)

Question 1

What is the anatomic dead space?

Answer 1

Those airways not designed to participate in gas exchange

Question 2

If airway resistance is HIGH…

Airflow

Answer 2

Slows down

Question 3

If airway resistance is LOW

Airflow is…

Answer 3

Fast and easy

Question 4

What equation gives insight into the resistance of the bronchiole?

Answer 4

Question 5

Changing the ______ has the greatest impact on the resistance to airflow

Answer 5

Radius

Question 6

What is average Perfusion (Q) value?

Answer 6

5 L blood per min

Question 7

What is the equation we use to measure diffusion of a gas?

Answer 7

Question 8

Under normal resting conditions:

What is the “J” for….

O2?

CO2?

Answer 8

O2= 250mL

CO2 =200mL

Question 9

The diffusion of each gas is _________ of one another

Answer 9

independent

Question 10

Which factors in the diffusion calculation depend directly on the structure of the alveolus?

Answer 10

Question 11

What is a disease state where “J” decreases?

Answer 11

COPD

SA decreases

Question 12

What disease would increase the distance for diffusion?

Answer 12

Interstitial lung diease

Question 13

Solubility (D) of CO2 is ______ that of DO2

Answer 13

20X

Question 14

What does (P1-P2) measure in the diffusion equation?

Answer 14

Question 15

Under resting contitions…

An RBC spends about ____ seconds in a pulmonary capillary

Answer 15

0.75

Question 16

How long does it take to “load” an RBC in a pulmonary capillary?

Answer 16

0.25 seconds

Question 17

During exercise….

How long does the RBC stay in the alveolar capillary?

Answer 17

0.25 seconds

Question 18

How do you measure the diffusion of O2? (DLO2)

Answer 18

USE CARBON MONOXIDE

Question 19

What is the correction factor for using carbon monoxide?

Answer 19

DL O2= 1.23 x DL CO

Question 20

What are the relative diffusion capacities of CO2 vs O2?

Answer 20

DLCO2 >>>>>>>>> DLO2

Question 21

Surfactant primarily acts on

Answer 21

Smallest alveoli