1.6 - Blood Clotting

Question 1

What is thrombosis?

Answer 1

blockage of artery through formation of a blood clot

Question 2

What is the formation of a blood clot?

Answer 2

Collagen exposed to damaged blood vessels
activation of platelets
platlets stick to exposed collagen
= platelet plug
Releases thromboplastin
Catalyses thrombin from prothrombin
catalyses fibrin from fibrinogen
cross links forms
RBCs and platelets trapped in fibrin mesh
blood clot forms

Question 3

What is a heart attack?
(narrowing in coronary arteries)

Answer 3

• less oxygen in cardiac muscle
• anaerobic respiration
• chest pain (angina)

Question 4

What is a heart attack?
(complete blockage)

Answer 4

• no blood supply of cardiac muscle
• cardiac muscle becomes ischaemic
  (without blood)
• heart attack (myocardial infarction)