1.6 Flashcards

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1
Q

what is cell metabolism

A

the collective term for the thousands of biochemical reactions that take place in a living cell

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2
Q

what are catabolic reactions

A

degradation, releases energy

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3
Q

what are anabolic reactions

A

synthesis, require energy

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4
Q

why are some metabolic pathways reversible and irreversible

A

to allow the process to be controlled precisely

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5
Q

why do some metabolic pathways contain alternative routes

A

to allow steps in the pathway to be bypassed

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6
Q

what indicates the the rate of a chem reaction

A

the amount of chemical change that occurs per unit of time

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7
Q

what is the chemical change

A

the joining together or breaking of reactant molecules

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8
Q

what is the energy needed to break chemical bonds

A

activation energy

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9
Q

what are enzymes

A

biological catalysts which speed up the rate of reactions by lowing the energy needed to form the transition state

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10
Q

what do enzymes allow biochem reactions to do

A

happen at low temperatures

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11
Q

what is the induced fit

A

when the substrate binds to the active site and it changes shape slightly to better fit the substrate

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12
Q

what is high affinity

A

a chemical attraction to the active site

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13
Q

what does an induced it do

A

lowers the activation energy by weakening the chemical bonds of the substrate molecule

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14
Q

do products have a low or high affinity to the active site

A

low

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15
Q

does the enzyme change during induced fit

A

no

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16
Q

how are the products of an enzyme reaction able leave the active site

A

they don’t have a high affinity which allows them to leave

17
Q

how does the induced fit lower the activation energy

A

by weakening the chemical bonds of the substrate molecules

18
Q

what determines the orientation of reactions

A

the shape of the active site

19
Q

what are the effects of substrate concentration

A

as the substrate concentration increases, the rate of enzyme reaction also increases until all active sites are occupied by substrates then it remains steady

20
Q

what effects the direction of enzyme reactions

A

substrate and product concentrations

21
Q

what happens if product concentration is too high

A

the enzyme can work in reverse to convert some of it back to the substrate

22
Q

what are the 3 inhibitors

A

competitive
non competitive
feedback

23
Q

where do competitive and non competitive inhibiters bind

A

competitive - at the active site
non competitive - away from the active site

24
Q

which inhibitors can be reversed by increasing substrate concentration

A

competitive

25
Q

when does feedback inhibition occur

A

when the end product in the metabolic pathway reaches a critical concentration

26
Q

describe events of feedback inhibition

A

the end product reaches a critical condition and then the end product inhibit an earlier enzyme, blocking the pathway and so and preventing further synthesis of the end product