1.5.1: Nucleic acid structure Flashcards

1
Q

state 2 functions of the DNA

A

1 - replication for cell division
2 - Carry genetic code for protein synthesis

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2
Q

State the 3 types of RNA and their full forms too

A

1 - mRNA - messenger RNA
2 - tRNA - transfer RNA
3 - rRNA - ribosomal RNA

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3
Q

What are the two types of nucleic acids

A

DNA and RNA

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4
Q

how many polynucleotides does a molecule of DNA contain and where is it found

A

2 - nucleus

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5
Q

how many polynucleotides does a molecule of RNA have and where is it found

A

1 - cytoplasm and nucleus

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6
Q

Describe the structure of a general nucleotide

A

pentose sugar (ribose or deoxyribose), nitrogenous base attached to carbon-1, phosphate group attached to carbon-5

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7
Q

what is the full form of ATP

A

adenosine triphosphate

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8
Q

what are the 2 types of nitrogenous bases

A

purine bases, pyrimidine bases

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9
Q

List the purine bases

A

adenine
guanine

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10
Q

list the pyrimidine bases

A

thymine
cytosine
uracil

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11
Q

what are 2 main differences between purine and pyrimidine bases

A

purine bases are always bigger than pyrimidine bases, purine bases are double ring whereas pyrimidine bases are single ring

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12
Q

which bases have complementary base pairing and how many h-bonds are there between each pair

A

A-T (2 H bonds)
C-G (3 H bonds)
A -U (2 H bonds)

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13
Q

What is the relation between purine and pyrimidine bases

A

they complementary base pair to each other

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14
Q

Describe the process of the formation of a DNA molecule

A

When a condensation reaction occurs between the pentose sugar of one nucleotide and the phosphate group of another, a strong covalent bond called a phosphodiester bond forms.
Repeated condensation reactions results in a single chain of repeating nucleotides which has a strong sugar-phosphate backbone with bases protruding from it. The second polynucleotide chain forms antiparallel to the first running from 5’ to 3’. Hydrogen bonds form between exposed bases that are complementary to each other joining the 2 polynucleotide chains together.

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15
Q

how is the feature of the DNA having a sugar-phosphate backbone related to its function

A

gives strength to the DNA molecule

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16
Q

how is the feature of the DNA being two chains held together by weak hydrogen bonds related to its function

A

chains can be separated for transcription and replication

17
Q

how is the feature of the DNA having a coiled structure related to its function

A

protects hydrogen bonds therefore reducing corruption of genetic code

18
Q

how is the feature of the DNA having many weak hydrogen bonds related to its function

A

makes DNA a stable molecule

19
Q

how is the feature of the DNA having a sequencing of DNA bases related to its function

A

allows information to be stored

20
Q

how is the feature of the DNA being a long molecule related to its function

A

can store a lot of genetic information

21
Q

what is the difference in the nitrogenous bases present in DNA and in RNA

A

RNA has uracil instead of thymine

22
Q

Name the 2 scientists who proposed models of the chemical structure of DNA

A

Watson and Crick