14 - Basic bone biology Flashcards
1
Q
role of osteoblasts?
A
formation of new bone
2
Q
role of osteoclasts?
A
breakdown/ resorption of bones
3
Q
which cells are a precursor for pre-osteoclasts?
A
myeloid progenitor cell
4
Q
which cells are a precursor for pre-osteoblasts?
A
mesenchymal progenitor cells
5
Q
which ligand regulates the osteoclast differentiation and activation?
A
RANK ligand
6
Q
what is the receptor for the RANK ligand?
A
RANK
7
Q
what is the role of vitamin D in forming and maintaining bone strength?
A
absorption of calcium
8
Q
name 4 organs which are involved in the hormonal regulation of calcium metabolism?
A
kidney, intestine, parathyroid glands, liver
