1.3 Flashcards

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1
Q

translation

A

mrna attaches to the ribosome
codons in the mrna code for a specific amino acid
transfer of amino acids to the ribosome by trna
anticodon on the trna matches codons on the mrna strand
amino acids are linked to form polypeptides by peptite bonds

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2
Q

transcription

A

sections of dna carying the gene to be transcribed unwinds
dna strands separate
antisense strand used as a template
rna polymerase binds to the non coding DNA located infront of the gene
rna polymerase produces a complimentary strand of the mrna from coding dna of a gene by complimentary base pairing
a-t
g-c
mrna leaves nucleus through nuclear pore

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3
Q

atp

A

energy supply for cells
nucleotide with three phosphate groups
when energy is needed the third phosphate group is broken in a hydrolysis reaction by the enzyme ATPase the product is adp
reaction releases energy

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4
Q

dna replication

A

two strands of DNA unzip and unravel
-dna helicase breaks hydrogen bonds
the strands act as templates
free nucleotide bases attract
phosphodiester bonds synthesised
-dna polymerase
complimentary nucleotides bind
hydrogen bonds form between AT GC
-dna ligase to join fragments

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5
Q

chromosomal mutations

A

changes in the position of genes within the chromasomes

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6
Q

whole chromasome mutation

A

an entire chromosome is lost during meiosis

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7
Q

dna bases

A

hydrgogen bonds between bases
at- 2 bonds
gc- 3 bonds

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8
Q

nucleotides

A

pentose sugar
nitrogen containing base
phosphate group
provides energy in the form atp
formed in a condensation reaction with the elimination of two water molecules

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9
Q

nucleic acid

A

polynucleotides
information needed to form new cells
found in dna then copied into mrna
direct the production of proteins
made in a condensation reaction
joined in a phosphodiester bond

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10
Q

gene mutation

A

one or a small number of nucleotides are miscopied

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11
Q

substituiton

A

one base substitutes for another

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12
Q

deletions

A

base completly lost

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13
Q

addition

A

extra base added

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14
Q

nucleotide bases

A

purine
2 nitrogen containing rings
a+g
pyrimidines
1 nitrogen containing ring
c+t+u

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15
Q

deoxyribose

A
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16
Q

sugar phosphate backbone

A

both dna and rna have one
dna has two polynucleotide strands and rna has one

17
Q

conservative

A

origional double helix stays intact
and instructs the formation of a new identical double helix

18
Q

semi conservative

A

dna is unzipped and new nucleotides line along each strand
each double helix consists of one origional and one new

19
Q

degenerate

A

more than one triplet for each amino acid

20
Q

non overlapping

A

each base is only part of one triplet (codon)

21
Q

phosphodiester bonds

A

between nucleotides
-pentose sugar and phosphate

22
Q

enzymes in dna replication

A

helicase
-unzips and unwinds breaking the hydrogen bonds
ligase
-lines up and catalyses the phosphodiester bonds joining fragments of DNA between phosphate and sugar
polymerase
-forms phosphodiester bonds joining the sugar-phosphate backbone

23
Q

why are dna bases more variable than the amino acid sequences

A

more triplet codes than amino acids
so code is degenerate
some amino acids may have a different code
maintaining structure of a protein

24
Q

modified molecule

A

5’ 3’ ends - dna code
inside molecule - mrna code

25
Q

hydrogen bond

A

between bases 5’ and 3’
hold two strands of DNA together in a double helix

26
Q

how are monomers bonded to a polypeptite chain

A

peptite bond between amino acid and carboxyl group
condensation reaction