1.11 Antivirals Flashcards
1
Q
What drugs block viral uncoating and what are they active against?
A
Amantadine and Rimantadine; active against Influenza A
2
Q
What is the most common mutation that leads to resistance to viral uncoating blocker drugs?
A
S31N mutation conveys resistance to Amantadine and Rimantadine
3
Q
What do neuraminidase inhibitors do?
A
Mimic sialic acid and prevent virion release
4
Q
What are the two neuroaminidase inhibitors and which has a shorter half-life?
A
Oseltamivir and Zanamivir; Zanamivir has a 3 hr half-life in the lungs
5
Q
What is Ribavirin used to treat?
A
Respiratory Syncytial Virus
6
Q
Why would you use epinephrine in a person with bronchiolitis?
A
Bronchodilator to help treat symptom
