11. exogen-allergische Alveolitis Flashcards

1
Q

(EAA)

Ätiologie (3)

A
  • Farmerlunge
  • Vogelharterlunge
  • Befeuchterlunge
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2
Q

(EAA)

Farmerlunge: Antigen

A

Aktinomyzeten

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3
Q

(EAA)

Vogelharterlunge: Antigen

A

Vogelproteine

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4
Q

(EAA)

Befeuchterlunge: Antigen

A

Wasserreservoirs

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5
Q

(EAA)

Pathophysiologie

A

kombinierte Typ-III- und -IV-Reaktion

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6
Q

(EAA)

Formen (2)

A
  • akutes Stadium
  • chronisches Stadium
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7
Q

(EAA)

Leitsymptom

A

rezidivierende “grippale Infekt” mit Reizhusten und Fieber

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8
Q

(EAA)

akute Form: Charakteristik

A

Beginn ca. 4h und Abklingen ca. 24h nach Exposition

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9
Q

(EAA)

chronische Form: Charakteristik

A

schleichende Zunahme

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10
Q

(EAA)

Befund bei der Auskultation

A

beidseitig betontes, basales inspiratorisches Knisterrasseln (Skleroiphonie)

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11
Q

(EAA)

Serologie

A

präzipitierende IgG-AK

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11
Q

(EAA)

Labor

A

Serologie

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12
Q

(EAA)

Bildgebungen der Wahl im chronischem Stadium (2)

A

Röntgen- oder CT-Thorax

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12
Q

(EAA)

Röntgen-Thorax-Befund

A

retikulonoduläre (netz- und feintüpfelige) Zeichnungsvermehrung

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13
Q

(EAA)

CT-Thorax-Befund

A

disseminierte, milchglasartige Eintrübungen in den basalen Lungenabschnitten

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14
Q

(EAA)

apparative Diagnostik

A

Lungenfunktion

15
Q

(EAA)

Lungenfunktionsbefund

A

primär restriktive Ventilationsstörung

16
Q

(EAA)

primär restriktive Ventilationsstörung: Leitbefund

A
  • verminderte VC
17
Q

(EAA)

weitere Diagnostik in unklaren Fällen

A
  • BAL
  • Biopsie
18
Q

(EAA)

BAL-Befund im akuten Stadium

A

Neutrophilie

19
Q

(EAA)

BAL-Befund im chronischen Stadium

A

CD8-Lymphozytose

(CD4/CD8-Quotient < 1)

20
Q

(EAA)

Biopsiebefunde (2)

A
  • intramurale Alveolitis mit lymphozytärem Infiltrat
  • granulomatöse Entzündung
21
Q

(EAA)

Therapie der Wahl

A

Glucocorticoide