10 11 13 14 Flashcards

1
Q

organ that is responsible for synthesis of coagulation factors

A

LIVER

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2
Q

25% of platelets can be found in which organ?

A

SPLEEN

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3
Q

___ plays a role in the formation of factor 9

A

CALCIUM

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4
Q

increase in Hg affinity for O occurs w/…

A

a shift to the left on the dissociation curve

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5
Q

a decrease in O affinity occurs w….

A

shift to the right on the oxyhemoglobin dissociation curve

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6
Q

what is the effect on resistance if the radius of a vessel is halved?

A

resistance increases by a factor of 16

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7
Q

normal BT, platelet

^PT/INR

A

vit K deficiency

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8
Q

vit K affects which pathway?

A

the extrinsic pathway of coagulation

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9
Q

telangiectasia

A

dilated or tortuous small blood vessel found in skin or mucous membrane

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10
Q

petechiae

A

pin point hemorrhage

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11
Q

purpura

A

collection of petechiae

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12
Q

when systemic vascular resistance is decreased, BF…

A

blood flow decreases

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13
Q

microcytic anemias

A

thalassemia + iron deficiency

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14
Q

hypochromic anemias

A

thalassemia + iron deficiency

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15
Q

macrocytic/megaloblastic anemias

A

b12 deficiency like pernicious

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16
Q

autologous stem cell transplant

A

stem cells harvested fr patient + returned to same patient

17
Q

primary immune deficiency that affects B cells

A

IgA

18
Q

treatment for anemia due to kidney failure

A

EPO administration + dialysis

19
Q

best treatment for CML

A

bone marrow transplant. NOT CHEMO

20
Q

Ph chromosome

A

CML

21
Q

bence jones protein

A

Plasma Cell Myeloma

22
Q

reed sternberg

A

Hodgkin

23
Q

HLA/MHC

A

protein found in cells that increase autoimmunity

24
Q

von willebrand FACTOR

A

plays role in platelet adhesion to injured site

25
Q

hyperemia

A

local increase in bloow flow

26
Q

transfusion rxn involve RBC hemolysis by____

A

RECIPIENT ANTIBODIES

27
Q

intermittent claudication

A

clinical manifestation of chronic arterial obstruction

–it is the loss of blood flow in legs