1. Wk 6 Chronic Inflammation

Question 1

origins of Chronic inflam

Answer 1

1. follows acute inflam
2. repeated attachs of acute inflam
3. begins insidiously

Question 2

What (3) sub will be present at an immune response ***

Answer 2

1. macrophage
2. lymcytes
3. plasma cells
   - the 3 cells that will identify chronic inflam

Question 3

What (3) sub activate macrophages to do phagocytosis

Answer 3

1. Y interferon
2. immunoglobulin
3. complement

Question 4

What (3) damaged tissues will be repaired

Answer 4

1. new blood vessels- cap.
2. fibroblasts
3. fibrosis

Question 5

What are three characteristics of Chronic inflam (5)

Answer 5

1. insidious onset
2. progressive
3. vasodilation: mild- no redness/hotness
4. scanty exudate: no edema
5. B & T lymphocytes, plasma cells & macrophages

Question 6

Does chronic inflam have exudate or transudate?

Answer 6

exudate

Question 7

Name (4) cinflam cells:

Answer 7

B & T lymphocytes
plasma cells
macrophages

Question 8

monocytes are ___

Answer 8

macrophages

Question 9

Monocyte phagocytosis is activated by (2)

Answer 9

immune: y interferon

non immun: bact endotoxin

Question 10

Monocytes are:

1. ___ size of cells
2. active ___
3. ____ enxymes

Answer 10

1. large in size
2. acitve metabolism
3. lysosomal enzymes

Question 11

Name (4) bact. killing oxygen kill radicals

Answer 11

O2
H2O2
HOCl
O3

• O2 independant = enzymes

Question 12

What are oxygen independant mech for killing bacteria

Answer 12

enzymes

Question 13

___cytes product fibroblast growth factor & T/B lymphocytes growth promoting factor

Answer 13

monocytes

Question 14

___: produce Antibodies agaisnt foreign antigens or modified tis antigen

Answer 14

plasma cells

Question 15

____: mobilized in both antibody and cell mediated immune rxn

Answer 15

lymphocytes

Question 16

___: immune rxn mediated by IgE & parasitic infections

Answer 16

eosinophils

Question 17

5 types of chronic inflam cells

Answer 17

1. monocytes
2. plasma cells
3. lymphocytes
4. eosinophils
5. neutraphils

Question 18

What are the two different types of granulomatous cells (2)

Answer 18

eitheloid cells - mod macrphages

giant cells

Question 19

20+ epitheloid cells will fuse together to make _____ cells

Answer 19

giant

Question 20

Name two types of giant cells

Answer 20

1. langhan’s giant cells

2. foreign body giant cells

Question 21

____ cells have a center of necrosis

Answer 21

granuloma

Question 22

4 types of cells located in the granuloma

Answer 22

1. peripheral rim of lymphocytes
2. plasma cells
3. neutrophils
4. collagen fibers

Question 23

(3) infections that are granulosum

Answer 23

1. TB
2. leprosy
3. syphilis

Question 24

Name 1 type of dx that is granulosum

Answer 24

silicon dust –> ex of foreign body gradnulosum

Question 25

Fever is caused by liberation of pyrogens: ___ & ____

Answer 25

IL-1 & TNF

Question 26

_____ is the heat regulating center in the brain

Answer 26

hypothalmus

Question 27

to cause a fever, the hypothalmus sends SP stim to the skin do to vaso____

Answer 27

vasoconstriction

- this will decrease heat loss = fever

Question 28

Leukocytes are released from ____

Answer 28

bone marrow

TNF & IL-1

Question 29

prolong infection stim bone marrow ____ cells

Answer 29

stem cells

Question 30

Name 4 rxns that will occur during a fever

Answer 30

sleepiness

decr. BP
incr. fibrinogen
incr. Erythrocyte sedimentation rate (ESR)

Question 31

If the lymph nodes failure to localize the inflam the infection will go to the blood ____ cells

Answer 31

reticuloendothelial cells