1 C Flashcards
The disease where a person cannot produce saliva is called what?
Xerostomia
What is the normal daily amount of saliva a person will produce?
800-1500 ml
What are the four diseases that can lead to xerostomia?
What are some other causes?
Diabetes
HIV/AIDS
Parkinsons Disease
Sjogrens Syndrome
Radiation therapy
Injury to the head and neck
What is the path a drop of saliva would follow from production to secretion?
Acinus- Intercalated duct- Striated duct
What are myoepithelial cells?
Elongated or star shaped non-secreting cells with long branching processes. When stimulated by neural input the cells contract to eject saliva into the mouth.
What are the three types of acini?
Serous, mucous, or mixed
What are the three main salivary glands and what percentage of daily saliva do each produce?
Parotid- (Serous) Watery 25%
Submandibular- (Mixed) Semi Viscous 71%
Sublingual- (Mucous) Viscous 3-4%
What duct drains the parotid gland?
Stensens Duct
What duct drains the Submandibular Gland?
Wharton’s Duct
What duct drains the sublingual gland?
Ducts of Rivinus
What is the composition of saliva?
- 5% water
0. 5% protein and electrolytes
What are the three most important salivary enzymes?
Salivary alpha amylase
Lingual lipase
Mucins
What type of bonds can salivary amylase cleave?
Internal alpha 1-4
What are the three constituents of saliva that give it its antibacterial properties?
Lysozyme
Lactoferrin
Immunoglobulin A
What are the benefits of normal oral flora?
Prevent colonization of pathogens by competing for attachment sites or essential nutrients
Antagonize other bacteria through the production of substances which inhibit or kill non-indigenous species
Stimulate the production of cross-reactive antibodies