05.20 - UTIs (Brint) - PP

Question 1

2 frequent causes of hematogenous UTI

Answer 1

Bacterial endocarditis, Indwelling venous catheters

Question 1

How can you tell if kidney is involved

Answer 1

WBC Casts

Question 2

Blood culture when pyelonephritis

Answer 2

Will be positive

Question 3

How does preganancy affect rate of pyelonephritis

Answer 3

Greatly increases

Question 3

Fever, Chills, Flank pain, CVAT =

Answer 3

Upper Tract Infection

Question 4

Catheter in bladder =

Answer 4

colonization w/ water-loving bacteria that start with P

Question 4

pH of 8 =

Answer 4

Urea-splitting bacteria (Struvite)

Question 4

Abx most effective in both Complicated and Uncomplicated UTI

Answer 4

Cipro

Question 5

Why is there an increased rate of UTI in pregnancy

Answer 5

Progesterone lowers motility –> Stagnate urine

Question 7

How does contraception affect rate of UTI

Answer 7

foreign body contraceptives increase rate

Question 8

2 Abx for Pyelonephritis that have lowest renal concentrations

Answer 8

Cephalothin, Ampicillin

Question 9

Abx most effective in complicated but not uncomplicated

Answer 9

Ceftriaxone, Gentamicin

Question 10

What percent of UTI bactereria come from GI

Answer 10

95%

Question 12

2 main causes of Dysuria

Answer 12

Classic Cystitus (50%), Acute Urethral Syndrome (40%)

Question 12

UTI + Obstruction =

Answer 12

Papillary Necrosis

Question 14

Male vs female in elderly

Answer 14

Male catch up due to impaired flow (BPH)

Question 15

Receptor for bacterial fimbriae on uroepithelium

Answer 15

P blood group antigen

Question 15

Painless hematuria =

Answer 15

Cancer

Question 16

Two most common organisms in UTI

Answer 16

E coli, Staph saprophyticus

Question 18

WBC casts indicate

Answer 18

kidney involvement

Question 19

Antibiotic duration in men vs women

Answer 19

Longer use in men because there must be something structural

Question 20

Frequent cause of altered mental status

Answer 20

Infection

Question 21

Recurrent gonorrhea causes

Answer 21

Urethral stricture

Question 22

Male vs female in infants

Answer 22

Male > Female

Question 23

Virulence factor that impairs phagocytosis

Answer 23

K antigen (capsular polysaccharides)

Question 25

Acute Urethral Syndrome vs Classic Cystitus

Answer 25

Classic is > 10^5 cfu/mL, Acute Urethral is

Question 27

Why do UTI’s more frequently progress in pregnant women?

Answer 27

Immunosuppressive state

Question 28

Struvite Renal Calculi occur in patients with

Answer 28

some abnormality of tract

Question 29

Organism in young females that aren’t too sick

Answer 29

Staph Saprophyticus

Question 30

T/F: Hematuria is a common feature of UTI

Answer 30

false, should be thinking more tubulointersitial disease

Question 31

Significant bacteruria is what amount

Answer 31

>15^5 cfu

Question 32

In Acute Urethral Syndrome, inflammatory response is limited to

Answer 32

the Urethra

Question 33

If multiple organisms in urine culture

Answer 33

Reported as contaminated (False positive)

Question 34

Role of Tamm-Horsfall in UTI

Answer 34

Thought that it may inhibit colononization and adherence

Question 35

2 signs of contaminated urine culture

Answer 35

Multiple organisms, Lots of squamous cells