03b: GI Motility Flashcards
There are two nerve plexi in GI tract. The myenteric plexus is in (X) tissue layer (be specific). Where is the second?
X = muscularis externa (between inner circular and outer long muscle layers)
Submucus nerve plexus in submucosa layer
Mastication’s purpose is to (increase/decrease) (X) of food.It is under (voluntary/involuntary) control.
Increase;
X = exposed surface area (to secretions)
Initially voluntary, but rhythmicity is reflexively maintained
What’s deglutition?
Transport/propulsion of bolus from mouth to stomach
Precise orchestration of movements of several structures is important in deglutition. List some nerves that are important here.
- CN VII, IX, X, XII;
2. Lingual and medial pterygoid nerves
Deglutition occurs in which phases?
- Oral
- Pharyngeal
- Esophageal
T/F: Initiation and continuation of swallowing is voluntary.
False - initiation is, but then swallowing is reflexly controlled
During swallowing, aka (X) phase of deglutition, (Y) closes (Z) so that food doesn’t go into nose.
X = oral Y = soft palate (elevation) Z = nasopharynx
During (X) phase of deglutition, UES opens to allow food into (Y). At this phase, it’s important to block food from entering which space(s)?
X = pharyngeal Y = esophagus
Airways
Passage of bolus into airways is prevented via which mechanisms?
- Larynx elevated (glottis closed)
- Epiglottis tilts downward
- Respiration stops briefly
During (X) phase of deglutition, peristalsis is important for propelling food toward (UES/LES).
X = esophageal
LES
Normally, (X) (contraction/relaxation) prevents reflux of gastric contents.
X = LES
Contraction
The velocity of peristaltic wave is normally (X).
X = 3-5 cm/s
T/F: Liquids can bypass the peristaltic wave due to gravity.
Ture
The primary esophageal peristalsis is associated with (X). The secondary esophageal peristalsis is associated with (Y).
X = original swallowing Y = residual bolus or reflux
Control of deglutition is coordinated by swallowing center in (X) part of brain. Sensory afferent inputs via (Y) nerves and efferents via (Z) nerves.
X = medulla Y = CN IX and X Z = CN X
Initiation of peristalsis in upper portion of esophagus is innervated (directly/indirectly) by (X) nerve.
Directly;
X = vagus
T/F: A peristaltic wave, once initiated, can proceed in vagally denervated esophagus.
True
In lower 2/3 of esophagus, propagation of bolus (via peristalsis) is principally dependent on (X) nerves.
X = plexus of neurons in wall
Innervation of esophagus by (X) is absolutely necessary for proper motility.
X = myenteric plexus
LES is under neural control. Excitatory via (X), inhibitory via (Y). Both influenced by (Z).
X = Y = myenteric plexus Z = vagus
T/F: Peristalsis only at lower esophagus will inhibit LES tone (opening of sphincter).
False - peristalsis at ANY level of esophagus
Vagus has excitatory influence on myenteric plexus via (X) NT and receptor. And it has inhibitory influence on myenteric plexus via (Y) NT and receptor.
Both excit and inhib preganglionic fibers from vagus release ACh and bind nicotinic receptors on myenteric plexus.
It’s the post-gang NT that make a difference
Excitatory post-ganglionic fibers of myenteric plexus release (X) transmitter that binds (Y) receptors.
X = ACh; Y = muscarinic
Inhibitory post-ganglionic fibers of myenteric plexus release (X) transmitter that binds (Y) receptors.
X = NO and VIP (vasoactive intestinal peptide) Y = no specific receptor..