03 - Breast lump

Question 1

Tripple screen for breast lump

Answer 1

Clinical exam + mammogram + biopsy in that order

Question 2

Screening for breast Ca ? Who has more aggressive screening?

Answer 2

women 50-70 are screened every 3 years

BRCA1/2
FHx

Question 3

Why is US better in younger women ?

Answer 3

denser breast tissue

Question 4

Some features of a benign breast lump?

Answer 4

Painless
mobile
smooth
well defined margins

Question 5

Features of a malignant breast lump

Answer 5

Painful 
tethered 
dishcharge 
rough edges 
poorly defined 

peau d’orange and other skin changes, nipple inversion, B sypmtoms, Paget’s

Question 6

Egs of benign breast lumps

Answer 6

Cysts, nodularity, fibroadenoma, fat necrosis, mastitis.

Question 7

Mx of breast lumps

Answer 7

Depends on staging, genetics, grading, histopathology

Surgical
Mastectomy, lumpectomy, quadranectomy

Recontructive

Radiotherapy

Chemo

Hormone

Question 8

Egs of chemo for breast

Answer 8

cyclophosphamide and doxorubicin

Question 9

Eg of hormonal therapy

Answer 9

tamoxifen (10 years),

letrozole (five years, but only post menopause)