x exam 2 vessel formation Flashcards
what is the major pathway to supply blood to body
dorsal aorta
dorsal aorta is initially ____ and runs _____
paired (left and right); length of hte embryo
left and right dorsal aorta _____ most of length of body
fuse to give single dorsal aorta
dorsal aorta form
vaculognesis and angiogenesis
mesoderm, dorsal to primitive gut (endoderm)
hear is ventrally located in embryo and developing gut is
interposed between heart and dorsal aorta
system of ___ aortic arches branch from ascending aorta around developing gut (pharyngeal region) to dorsal aorta
6 pairs
1st pair of aortic arches do what
disappear in development
2nd pair of aortic arches do what
disappear in development
3rd pair of aortic arches form
common carotid arteries
4th pair of aortic arches form
left: aortic arch and left subclavian artery
right: right sublcavian artery
5th pair of aortic arches
usually absent in mammals
6th pair of aortic arches form
left: left pulmonary artery; ductus arteriosus
right: right pulmonary artery
ventral unpaired branches off the developing dorsal aorta include
celiac, cranial mesenteric, caudal mesenteric
lateral paired branches from dorsal aorta form vessels to supply
adrenal glands (phrenicoabdominal, +/- separate adrenal artery) gonads (testicular ovarian) kidneys (renal)
dorsolateral paired branches of dorsal aorta include
intersegmental arteries that supply body wall, vertebral column, spinal cord and pelvic limbs including vertebral arteries, intercostal arteries, lumbar arteries
caudal most pair of lumbar arteries gives rise to
umbilical artery, external and internal iliac artery
vein formation: ___ systems develop
3; vitelline, umbilical, and cardinal
vitelline system drains
GIT and gut derivatives
vitelline system forms
liver sinusoids
hepatic portal system
part of caudal vena cava
ductus venosus
vitelline system develops in the
yolk sac
umbilical system develops in the
allantois
umbilical system carries _____ blood from _____ to ____
oxygenated blood from placenta to developing fetus
umbilical system initially forms
right and left umbilical vein; right disappears and left anastomoses with ductus venosus of liver
cardinal system develops in and drains
rest of the embryo (head, neck, and body wall)
cardinal system series of complex systems begin as
bilaterally symmetrical
cardinal system anastomoses,
loss of one side, or other, or both occurs
cardinal system persists as
caudal vena cava, azygous system
hematopoiesis
process of blood cell formation
blood islands are formed from
yolk sac mesoderm, 1st source of blood cells
core of embryonic hemoblasts surrounded by
endothelial cells
when do primitive blood cells circulate
as soon as connections are established
blood cell fomration in organs lasts for
a majority of gestation, ceases by birth
blood cells formed in organs
RBC and WBC stem cells
Liver, spleen, thymus
finally, ____ forms blood cells
bone marrow (major source in last trimester to adulthood)
vasculogenesis
new vessel, de novo
angiogenesis
growth, sprouting of a vessel to a target
steps in vasculogenesis
- core embryonic hemoblasts surrounded by flattened endothelial cells (blood islands) - endothelial cells join to form blood vessels, then vessel precursors lengthen and interconnect
similar process occurs in mesoderm of embryo, forming ______ giving rise to _____
angiogenic cords giving rise to dorsal aorta and aortic arches
angiogenesis
angioblasts to angiocytes to angiogenic cords to blood vessels
once started, process is ____ driven
target
minor vessels
support membrane tissue, no exchange (pnly vessels in amnion and non-placental chorion)
major vessels
transport to /from embryo body (yolk sac and allantoic membrane)
exchange vessesl
placental chorion
where chorion in contact with yolk sac
choriovitelline placenta
where chorion in contact with allantois
chorioallantoic placenta
yolk sac responsible for
nutrient exchange (not associated with chorion)
chorion associated with
gas exchange
connect areas of chorion and allantois responsible for
transport
angiocytes
endothelial cells