Neuro I Flashcards

1
Q

duplication at 2 cell blastocyst stage

A

2 separate sets of fetal membranes

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2
Q

duplication of inner cell mass

A

free twins of two separate embryonic discs; asymmetrical if unequal separation;
shared fetal yolk sac and chorion

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3
Q

gastrula: complete duplication of primitive streak

A

conjoined (tissues/organs)
symmetrical (2 complete, separate axes)
2 heads and vertebral columns

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4
Q

gastrula: incomplete duplication of primitive streak

A

conjoined, symmetrical; duplicated region 2 axes
unduplicated region; 1 axis;
at gastrula, all fetal membranes shared

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5
Q

duplication of gastrula without duplication of primitive streak

A

conjoined, asymmetrical
1 axes
other body tissues/ parts duplicated
especially limbs

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6
Q

what is the notochord

A

mesodermal rod;

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7
Q

notochord begins at

A

primitive node - deep to it and ectoderm

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8
Q

notochord oriented

A

craniocaudal along midline of longitudinal axis of embryo

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9
Q

notochord expands

A

cranial and caudal

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10
Q

as the notochord expands caudally, primitive streak ____

A

disappears

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11
Q

paraxial mesoderm

A

next to axis; mesodermal columns or bands, located on either side of notochord

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12
Q

what forms the paraxial mesoderm

A

somites from left and right pairs

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13
Q

somites form _____

A

sequentially from cranial to caudal

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14
Q

which forms first

A

cranial most pair

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15
Q

somites give rise to

A

segmental skeletal/connective tissue structures and muscle units (pattern imposed on developing peripheral nervous system)

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16
Q

first several fuse and contribute to

A

head structures

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17
Q

canine somites caudal to head include

A
8 cervical
13 thoracic
7 lumbar
3 sacral
10-20 caudal
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18
Q

notochord and paraxial mesoderm together begin

A

NS development

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19
Q

overlying ectoderm induce

A

neurectoderm (ectoderm above the notochord)

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20
Q

rest of ectoderm (surface ectoderm)

A

becomes epidermis

21
Q

neuroectoderm gives rise to

A

neural plate

22
Q

neuronal progenitors

23
Q

glial progenitors

A

astrocytes, oligodendrocytes, etc (excludes microglia)

24
Q

ependymal cells

A

line tubes and ventricles

25
formation of primary neural tube is the formation of
brain and majority of psinal cord and associated nerves
26
primary neural tube develops from
neural plate
27
neural plate is
proliferation and thickening of neuroectoderm
28
majority of the neural plate is
CNS
29
neural crest cells at edge of neural plate
PNS
30
Neural folds do what
elevate and grow toward each other at lateral edges
31
center of neural plate does what
sinks along long axis of body to from neural groove
32
neural crest cells are found at the junction of
neuroectoderm and surface ectoderm
33
as neural folds continue to grow toward one another, what happens to the neural groove
deepens
34
neural folds fuse to become
neural tube
35
neural tube created is a complete circle of
complete circle of neuroepithelium surrounding a neural canal
36
neural cres cells isolate from
neuroepithelium of neural tube and surface ectoderm, located between them on either side of the axis
37
surface ectoderm meets and fuses above
neural structures
38
fusion begins in the center and extends
outward along body axis in both directions (cranially and caudally)
39
chicks develop from
a single intitial fusion point while mammals tend to have multiple initial fusion points
40
openings at rostral and caudal ends are
rostral neuropore and caudal neuropore
41
primary neurulation is complete when
rostral and caudal neuropores are closed
42
secondary neurulation begins after
closure of caudal neuropore and completion of primary neurulation
43
located at about the _____ pair of somites
35th
44
secondary neural tube arises from
neuroectodermal cells of the tail bud or caudal eminence
45
proliferation and condensation of cells
x
46
caviation
forming a central cavity or lumen
47
fuses with caudal end of
primary neural tube
48
lumen becomes conitnuous with
neural canal
49
neural canal
ventricular system