Neuro I Flashcards

1
Q

duplication at 2 cell blastocyst stage

A

2 separate sets of fetal membranes

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2
Q

duplication of inner cell mass

A

free twins of two separate embryonic discs; asymmetrical if unequal separation;
shared fetal yolk sac and chorion

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3
Q

gastrula: complete duplication of primitive streak

A

conjoined (tissues/organs)
symmetrical (2 complete, separate axes)
2 heads and vertebral columns

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4
Q

gastrula: incomplete duplication of primitive streak

A

conjoined, symmetrical; duplicated region 2 axes
unduplicated region; 1 axis;
at gastrula, all fetal membranes shared

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5
Q

duplication of gastrula without duplication of primitive streak

A

conjoined, asymmetrical
1 axes
other body tissues/ parts duplicated
especially limbs

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6
Q

what is the notochord

A

mesodermal rod;

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7
Q

notochord begins at

A

primitive node - deep to it and ectoderm

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8
Q

notochord oriented

A

craniocaudal along midline of longitudinal axis of embryo

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9
Q

notochord expands

A

cranial and caudal

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10
Q

as the notochord expands caudally, primitive streak ____

A

disappears

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11
Q

paraxial mesoderm

A

next to axis; mesodermal columns or bands, located on either side of notochord

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12
Q

what forms the paraxial mesoderm

A

somites from left and right pairs

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13
Q

somites form _____

A

sequentially from cranial to caudal

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14
Q

which forms first

A

cranial most pair

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15
Q

somites give rise to

A

segmental skeletal/connective tissue structures and muscle units (pattern imposed on developing peripheral nervous system)

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16
Q

first several fuse and contribute to

A

head structures

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17
Q

canine somites caudal to head include

A
8 cervical
13 thoracic
7 lumbar
3 sacral
10-20 caudal
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18
Q

notochord and paraxial mesoderm together begin

A

NS development

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19
Q

overlying ectoderm induce

A

neurectoderm (ectoderm above the notochord)

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20
Q

rest of ectoderm (surface ectoderm)

A

becomes epidermis

21
Q

neuroectoderm gives rise to

A

neural plate

22
Q

neuronal progenitors

A

neurons

23
Q

glial progenitors

A

astrocytes, oligodendrocytes, etc (excludes microglia)

24
Q

ependymal cells

A

line tubes and ventricles

25
Q

formation of primary neural tube is the formation of

A

brain and majority of psinal cord and associated nerves

26
Q

primary neural tube develops from

A

neural plate

27
Q

neural plate is

A

proliferation and thickening of neuroectoderm

28
Q

majority of the neural plate is

A

CNS

29
Q

neural crest cells at edge of neural plate

A

PNS

30
Q

Neural folds do what

A

elevate and grow toward each other at lateral edges

31
Q

center of neural plate does what

A

sinks along long axis of body to from neural groove

32
Q

neural crest cells are found at the junction of

A

neuroectoderm and surface ectoderm

33
Q

as neural folds continue to grow toward one another, what happens to the neural groove

A

deepens

34
Q

neural folds fuse to become

A

neural tube

35
Q

neural tube created is a complete circle of

A

complete circle of neuroepithelium surrounding a neural canal

36
Q

neural cres cells isolate from

A

neuroepithelium of neural tube and surface ectoderm, located between them on either side of the axis

37
Q

surface ectoderm meets and fuses above

A

neural structures

38
Q

fusion begins in the center and extends

A

outward along body axis in both directions (cranially and caudally)

39
Q

chicks develop from

A

a single intitial fusion point while mammals tend to have multiple initial fusion points

40
Q

openings at rostral and caudal ends are

A

rostral neuropore and caudal neuropore

41
Q

primary neurulation is complete when

A

rostral and caudal neuropores are closed

42
Q

secondary neurulation begins after

A

closure of caudal neuropore and completion of primary neurulation

43
Q

located at about the _____ pair of somites

A

35th

44
Q

secondary neural tube arises from

A

neuroectodermal cells of the tail bud or caudal eminence

45
Q

proliferation and condensation of cells

A

x

46
Q

caviation

A

forming a central cavity or lumen

47
Q

fuses with caudal end of

A

primary neural tube

48
Q

lumen becomes conitnuous with

A

neural canal

49
Q

neural canal

A

ventricular system