wrong1 Flashcards

1
Q

MOA phenoxybenzamine

A

irriversible a1-2 blkr

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2
Q

FXN of a2 receptors

A

decrease sypa, insulin, lipolysis, aqueous, Increase PLT aggregation

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3
Q

how does allosteric activator effect the curve

A

shifts to lft but Vmax(height) stays the same

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4
Q

what are the key components of tight junctions

A

claudins/occludins

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5
Q

what are def in SCID/what’s MC

A

IL2 receptor gamma(MC), adenosine deaminase

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6
Q

how does the DTap work

A

it denature bacterial products

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7
Q

what antiporter helps restore K+ due to insulin use

A

Increase activity of H+/K+ antiporter in the a-intercalated cells. causes REABSORPTION of K+ but get rids of H+

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8
Q

what responds to HYPERKALIMIA in kidney

A

luminal K+ channels in principal cells causes EXcretion of K+

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9
Q

what’s DOC for lyme diz in prego/nursing women

A

AMOXICILLIN

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10
Q

DOC for Ghono in prego

A

cetriaxone & azithro

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11
Q

what’s the problem w/ Romano/Jervell syndrome

A

Long QT due mutation in myocardial K+ channel

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12
Q

Diff btwn Romano & HCM

A

Romano has TORSADE

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13
Q

Describe paget’s of bone

A

WOVEN bone (paget likes to weave)

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14
Q

what ion problem will cause a QT prolongation

A

hypocalcemia

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15
Q

what ion problem will cause a PR prolongation

A

HYPERKALAMIA

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16
Q

what hookworm cause Fe+ def

A

Necator Americanus

17
Q

what does it mean when u hv a lower blood gas partition coefficient

A

Lower solubility in blood=FAST RECOVERY

18
Q

low MAC=

A

LIPID soluble HIGH POTENCY

19
Q

Splitting is ass w/ what personality disorder

A

borderline(inability to mantain interpersonal relationships) etc

20
Q

what is the problem in aromatase def

A

unable to convert androgens to estrogens. mom probably had virilization(hisutism) during prego & child will hv virizilation also. Tall, amigous genitalia,