AssesUw1 Flashcards
what is Mosaicism
X diff cell lines
what is germline mosaicism
involves oocytes/spermatocytes (CHILD HAS IT but parents do NOT
what artery is affected in posterior tibia dislocation
POPLITEAL(also primary BS for calf/foot)
postpardum endometritis is MC in what structure
UTERUS
Sublimation
when u channel unacceptable thoughts/impulses to socially acceptable behavior
what ions does salivary gland has low/high of
LOW=Na+ Cl-
HIGH=K+
timeline for acute stress disorder
> 3days<1mo
ARR
control rate - treatment rate
what is the SERUM K+/NA in DKA
High=K+
Low=Na+
LH, FSH, TESTO in AIS
46XY but female PHENOTYPE HIGH=LH, TESTO
LOW=FSH
how does Nitrates effect HR/LVEDV
INCREASE HR, DECREASE LVEDV
CF has what ions lvl in sweat
INCREASE Na+/Cl
CF has what ions lvl in respiratory
secretions are LOW in Na+/Cl
problem w/ Pseudohypoparathyroidism
end organ resistance to PTH
lab values/presentation of pseudohypoPTH
Ca+ LOW
PTH, PO4= HIGH
short stature/fingers round face
what’s an AD form of pseudohypoPTH (MOM)
Albright Hereditary Osteodystrophy(GNAS1) codes for a of Gs protein(mediates effects of PTH)
DNA LOOPS are only form after what
RNA splicing has occured (removal of introns)
ELISA is used to do what
specific antibodies(IgG peroxidase)
what’s a common cause of bacteria multi drug resistance
EFFLUX PUMPS
Bruton is caused by what defect
BTK gene on X-chromo
what does proteins destined for the RER posses & if they don’t hv it where does it accumulate
they hv HYDROPHOBIC N-Terminal peptide signal sequence. IF they DON’T hv they accumulate in the CYTOSOL
what can cause howel jolly bodies
asplenia(surgically removal)/SS
what cell is effected if you have a low Testo in seminiferous/epididymis
SERTOLI
what receptor does the liver/glucagon EPI use for gluconeogeesis, glycogenolysis
Gs
what ABG does PE cause
RESPIRATORY ALKALOSIS
Hypoglycemia/LOW KETONES after fasting suggest what
impaired beta oxidation Medium chain Acyl-Coa dehydrogenase def.
chromogranin/synaptophysin is a marker for what tumor
Carcinoid(5HT) GI/LUNG
what DM drugs use SGLT-4
PIOGLITAZONE(PPAR-Y)
MOA LACTULOSE
acidifies GI convert NH3 to NH4 so it can be EXcreted
what second mesenger/receptor is stimulated to cause BRONCHODIALATION
B2/Increase cAMP
you have a decrease in what in OSTEOMALACIA(VIT D)
mineralazation of OSTEOID
what are the mjr risk factors for Peripheral Arterial Disease
DM, Smoking, HTN, hyperchol.
presentation of peripheral arteriosclerosis
pts have pain w/leg elevation prefer to sleep in a chair
what does germline of a pt that has a family of Li-fraumen shows
INACTIVATING(p53 should be activated) mutation affecting 1 allele
what are the muscles L.reccurent laryngeal nerve provide innervation to what muscles
Post./Lat CRICOARYTENOID
Oblique/Tranverse ARYTENOID
THYROARYTENOID
Hoarseness due to aortic arch aneurysm is due to what nerve
Left Recurrent Laryngeal
what nerve does the cricothyroid
External Laryngeal(VAGUS)
ALL DNA virus replicate where EXCEPT for
NUCLEUS except for POX
RNA viruses replicate where EXCEPT for
CYTOPLASM except for Retro(HIV), Orthomyxo
what’s the level of O2 in SVC
LOW
what causes ACHALASIA
infla/degeneration of neurons in ESO wall
PTS w/Broca stroke can present w/
expressive motor aphasia/ slow speech w/agrammatism. but understand spoken language/follow commands
what has unmyelinated nerve fibers
postganglionic autonomic nervous system, afferent neurons (heat sensation/slow onset dull burning/visceral pain
what size are unmyelinated fibers/are they slow or fast
sml diameter/slow
what does Pacinian corpusles mediate
touch/vibratory sensation
what MHCII component that is digested by macro during APC
INVARIANT CHAIN
Beta-2 microglobulin is used by what MHC
MHCI
PAS+ is ass w/ what diz
Whipple
MOA phenyleprine
a1>a2 agonist
what causes a dilation in the spermatic pampiniform plexus that enlarges w/standing & regress w/lying down
VARICOCELE
Long term Leuprolide use causes
DECREASE TESTO SYNTHESIS
what are the cardiac problems w/ DiGeorge
Truncus arteriosus, TOF, interrupted aortic arch
what is transformation
bacteria tk up naked DNA from environment (Haemophilus, strep, bacilus, Neisseria)
what is the SERUM for Nephro DM osmolality, ADH, NA+
SERUM=HIGH
URINE OSMOLALITY is LOW
Ehtylene glycol can cause what type of stones
Ca+ oxalate(dumbell/envelope)
ANION GAP ACIDOCIS
what structure is mostly effected in Acute RHINOSINUSITIS
Maxillary(middle nasal meatus)
what leads to the eustachian tube from the middle ear/ obstruction can cause what
NASOPHARYNX/OTITIS MEDIA
MCA causes what type of eye defect
H.H
which Band lenghtens during muscle relaxation/shortens during contraction
the I band ( the dark line before the end)
where are the thick filaments located
in the A band(lighter one)
what medication can you give to help pass a stone
Tamsulosin(a-antagonist) Nifedipine(ca+blkr)
where do stones mostly get stuck
VESICOURECTAL(narrowest)